Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971265 | 0.91 | SMN1; SMN2 (0.42) | SMN1; SMN2AGERALDH1A1GAAMAPT | |
| SCHEMBL8970849 | 0.89 | KDM4E (0.50) | SMN1; SMN2MTNR1AMTNR1BCYP1A2CYP2C9 | |
| SCHEMBL8971117 | 0.87 | AGER (0.47) | SMN1; SMN2CYP3A4AGERALDH1A1GAA | |
| SCHEMBL8970918 | 0.86 | MTNR1B (0.43) | SMN1; SMN2MTNR1AMTNR1BCYP1A2CYP2C9 | |
| SCHEMBL8971536 | 0.82 | MGAT2 (0.44) | MTNR1AMTNR1BCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7354465 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2MTNR1AMTNR1BCYP1A2CYP2C9 | |
| SCHEMBL8970733 | 0.80 | AGER (0.43) | SMN1; SMN2CYP3A4AGERALDH1A1GAA | |
| SCHEMBL8971050 | 0.74 | PGK1 (0.39) | SMN1; SMN2AGERALDH1A1MAPTRAB9A | |
| SCHEMBL7350242 | 0.72 | SMN1; SMN2 (0.43) | SMN1; SMN2AGERALDH1A1MAPTKMT2A | |
| SCHEMBL8603828 | 0.72 | MTNR1A (0.38) | SMN1; SMN2MTNR1AMTNR1BCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |