Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970849 | 0.91 | KDM4E (0.50) | MTNR1BKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8971982 | 0.86 | SMN1; SMN2 (0.41) | MTNR1BKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8971117 | 0.86 | AGER (0.47) | KDM4EALDH1A1AGERLMNAPOLB | |
| SCHEMBL8971536 | 0.83 | MGAT2 (0.44) | MTNR1BKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL7348962 | 0.81 | ALDH1A1 (0.45) | MTNR1BKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8970733 | 0.79 | AGER (0.43) | KDM4EALDH1A1AGERLMNAPOLB | |
| SCHEMBL8971265 | 0.79 | SMN1; SMN2 (0.42) | ALDH1A1AGERLMNAKMT2AMAPT | |
| SCHEMBL8971050 | 0.76 | PGK1 (0.39) | KDM4EALDH1A1AGERLMNAPOLB | |
| SCHEMBL7352264 | 0.73 | KDM4E (0.52) | MTNR1BKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8601552 | 0.71 | KDM4E (0.39) | MTNR1BKDM4EALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |