Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971982 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1KMT2AMAPTAGER | |
| SCHEMBL8971536 | 0.90 | MGAT2 (0.44) | ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL8971117 | 0.85 | AGER (0.47) | SMN1; SMN2ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL7350242 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL8970849 | 0.82 | KDM4E (0.50) | SMN1; SMN2ALDH1A1KMT2AMAPTCA1 | |
| SCHEMBL8970918 | 0.79 | MTNR1B (0.43) | SMN1; SMN2ALDH1A1KMT2AMAPTAGER | |
| SCHEMBL8970733 | 0.78 | AGER (0.43) | SMN1; SMN2ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL8971050 | 0.73 | PGK1 (0.39) | SMN1; SMN2ALDH1A1KMT2AMAPTCA1 | |
| SCHEMBL7354465 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1MAPTHPGDAGER | |
| SCHEMBL7359351 | 0.72 | MGAT2 (0.47) | SMN1; SMN2ALDH1A1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |