Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 5/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993010 | 0.88 | GPR52 (0.47) | KMT2ANPC1RAB9AMEN1LTA4H | |
| SCHEMBL8992766 | 0.87 | LTA4H (0.46) | FYNKMT2ANPC1RAB9AKDR | |
| SCHEMBL8993005 | 0.73 | LTA4H (0.49) | KMT2AMEN1LTA4HNR3C2BRS3 | |
| SCHEMBL8993194 | 0.73 | PLA2G2A (0.44) | FYNKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8993105 | 0.72 | BRS3 (0.45) | FYNNPC1RAB9AMAPTKDR | |
| SCHEMBL8993365 | 0.71 | MPO (0.44) | KMT2AMEN1LTA4HMPO | |
| SCHEMBL8992946 | 0.67 | MAPKAPK2 (0.46) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL8093981 | 0.66 | TAAR1 (0.46) | LTA4HMPO | |
| SCHEMBL23008755 | 0.66 | NR3C2 (0.43) | FYNLTA4HNR3C2 | |
| SCHEMBL8992912 | 0.65 | ACHE (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |