Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993063 | 0.84 | CALM1 (0.41) | LTA4H | |
| SCHEMBL2554823 | 0.79 | ALDH1A1 (0.43) | CTSBCTSLCTSSTAAR1 | |
| SCHEMBL2553737 | 0.75 | ALDH1A1 (0.40) | KDM4E | |
| SCHEMBL8093804 | 0.74 | TAAR1 (0.56) | DAOLTA4HMAOBSAE1UBA2 | |
| SCHEMBL15330263 | 0.74 | CYP2A6 (0.44) | KDM4ETAAR1 | |
| SCHEMBL17521457 | 0.74 | MAOA (0.54) | DAOLTA4HMAOAMAOBSAE1 | |
| SCHEMBL8992963 | 0.72 | LTA4H (0.46) | DAOKDM4ELTA4HSAE1UBA2 | |
| SCHEMBL20257530 | 0.72 | LOXL2 (0.48) | KDM4ELTA4HSAE1UBA2TAAR1 | |
| SCHEMBL9413533 | 0.71 | LTA4H (0.44) | DAOLTA4HSAE1UBA2TAAR1 | |
| SCHEMBL11087087 | 0.71 | LTA4H (0.53) | DAOLTA4HMAOBSAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |