Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907160 | 0.87 | ATM (0.43) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL476607 | 0.84 | ATM (0.47) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL1224158 | 0.84 | ATM (0.44) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL36569 | 0.83 | ATM (0.46) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL845109 | 0.83 | ATM (0.46) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL2141513 | 0.83 | ATM (0.46) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL2672114 | 0.83 | ATM (0.46) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL692375 | 0.83 | ATM (0.46) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL1001350 | 0.83 | ATM (0.46) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL66085 | 0.81 | ATM (0.44) | ATMHCAR2MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0969789-B2 | DENTAL MATERIALS HAVING A NANOSCALE FILLER | DENTSPLY INT INC (US) | 2015-08-19 | — | — | EP | claimed |
| EP-0969789-B1 | DENTAL MATERIALS HAVING A NANOSCALE FILLER | DENTSPLY INT INC (US) | 2006-08-09 | — | — | EP | claimed |
| US-6693143-B2 | ABRASIVE RESISTANCE AND THE COMPRESSIVE STRENGTH, RESISTANCE TO MICROLEAKAGE AND HAVE INCREASED BOND STRENGTHS | DENTSPLY DETREY GMBH (DE) | 2004-02-17 | — | — | US | claimed |
| EP-1024778-B1 | PROTECTIVE VARNISH FOR DENTIN | DENTSPLY INT INC (US) | 2003-09-17 | — | — | EP | claimed |
| US-6399037-B1 | LOW VISCOSITY NONSETTLING SURFACE METHACRYLOXYPROPYL HALOSILANE SILANIZED; STABLE SOL; ABRASIVE RESISTANT; INCREASED COMPRESSION AND BONDING STRENGTH; VARNISHES, SEALANTS, AND BONDING AGENTS | DENTSPLY DETREY GMBH (DE) | 2002-06-04 | — | — | US | claimed |
| US-20020065337-A1 | Dental materials having a nanoscale filler | DENTSPLY DETREY GMBH. | 2002-05-30 | — | — | US | claimed |
| US-20010009931-A1 | Protective varnish for dentin | PFLUG KAI (DE) | 2001-07-26 | — | — | US | claimed |
| EP-1024778-A1 | PROTECTIVE VARNISH FOR DENTIN | DENTSPLY INTERNATIONAL, INC. (US) | 2000-08-09 | — | — | EP | claimed |
| EP-0969789-A2 | DENTAL MATERIALS HAVING A NANOSCALE FILLER | DENTSPLY INTERNATIONAL, INC. (US) | 2000-01-12 | — | — | EP | claimed |
| WO-1999020227-A1 | PROTECTIVE VARNISH FOR DENTIN | DENTSPLY INTERNATIONAL INC. (US) | 1999-04-29 | — | — | WO | claimed |
| WO-1999017716-A2 | DENTAL MATERIALS HAVING A NANOSCALE FILLER | DENTSPLY INTERNATIONAL INC. (US) | 1999-04-15 | — | — | WO | claimed |
| EP-3335689-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2025-03-19 | — | — | EP | disclosed |
| US-20250082550-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DENTSPLY SIRONA INC. (US) | 2025-03-13 | — | — | US | disclosed |
| US-12023392-B2 | Additive manufacturing process | DENTSPLY SIRONA INC. (US) | 2024-07-02 | — | — | US | disclosed |
| US-20240180791-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2024-06-06 | — | — | US | disclosed |
| US-20010009931-A1 | Protective varnish for dentin | PFLUG KAI (DE) | 2001-07-26 | — | — | US | disclosed |
| EP-1024778-A1 | PROTECTIVE VARNISH FOR DENTIN | DENTSPLY INTERNATIONAL, INC. (US) | 2000-08-09 | — | — | EP | disclosed |
| EP-0969789-A2 | DENTAL MATERIALS HAVING A NANOSCALE FILLER | DENTSPLY INTERNATIONAL, INC. (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1999020227-A1 | PROTECTIVE VARNISH FOR DENTIN | DENTSPLY INTERNATIONAL INC. (US) | 1999-04-29 | — | — | WO | disclosed |
| WO-1999017716-A2 | DENTAL MATERIALS HAVING A NANOSCALE FILLER | DENTSPLY INTERNATIONAL INC. (US) | 1999-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240180791-A1 | DENTAL COMPOSITION | CAD, MTR, ESD | ATM 749/4885HCAR2 1649/4885MAPT 822/4885 |
| US-12023392-B2 | Additive manufacturing process | FLNA, FLNB, SAMM50 | ATM 4060/4885HCAR2 3902/4885MAPT 1152/4885 |
| US-20250082550-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DUOX2, DUOX1, QSOX1 | ATM 3141/4885HCAR2 2173/4885MAPT 3525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.