SCHEMBL921218

SCHEMBL921218

CCCC[CH]c1ccco1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.48
MAPT P10636 10/20 0.40
POLB P06746 8/20 0.40
MEN1 O00255 7/20 0.40
KMT2A Q03164 7/20 0.40
L3MBTL1 Q9Y468 5/20 0.40
HPGD P15428 4/20 0.40
LMNA P02545 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
GAA P10253 3/20 0.40
BLM P54132 2/20 0.40
CYP2C19 P33261 4/20 0.39
RECQL P46063 3/20 0.39
THRB P10828 3/20 0.39
CYP1A2 P05177 3/20 0.39
CYP2C9 P11712 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
CYP3A4 P08684 2/20 0.39
ALOX12 P18054 2/20 0.39
USP2 O75604 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL499995 0.94 ALDH1A1 (0.50) ALDH1A1MAPTPOLBMEN1KMT2A
SCHEMBL11842565 0.92 ALDH1A1 (0.49) ALDH1A1MAPTPOLBMEN1KMT2A
SCHEMBL3384654 0.92 ALDH1A1 (0.49) ALDH1A1MAPTPOLBMEN1KMT2A
SCHEMBL270347 0.88
SCHEMBL270295 0.81
SCHEMBL28304721 0.79
SCHEMBL497949 0.78 ALDH1A1 (0.41) ALDH1A1MAPTMEN1KMT2AL3MBTL1
SCHEMBL28235743 0.77 ALDH1A1 (0.48) ALDH1A1MAPTPOLBMEN1KMT2A
SCHEMBL8091560 0.76 ALDH1A1 (0.46) ALDH1A1MAPTPOLBMEN1KMT2A
Tetradecane SCHEMBL20557041 0.74 ALDH1A1 (0.69) ALDH1A1MAPTPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718281-B1 CYCLOHEXANEDIUREA DERIVATIVE AND PROCESS FOR PRODUCING THE SAME NISSIN FOOD PRODUCTS LTD (JP) 2001-06-27 EP claimed
CN-108140545-A Ultra-high modulus and etch selectivity boron-carbon hard mask film 应用材料公司 2018-06-08 CN disclosed
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20100324091-A1 Pyrazolone Derivative KOWA COMPANY, LTD. (JP) 2010-12-23 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2172458-A1 PYRAZOLONE DERIVATIVE Kowa Company, Ltd. (JP) 2010-04-07 EP disclosed
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-18 US disclosed
WO-2008126684-A2 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-23 WO disclosed
CN-100400707-C Method for hardening low dielectric constant film by electron beam APPLIED MATERIALS INC (US) 2008-07-09 CN disclosed
CN-101122011-A Methods for low temperature deposition of an amorphous carbon layer APPLIED MATERIALS INC (US) 2008-02-13 CN disclosed
CN-1930320-A Liquid precursors for chemical vapor deposition of amorphous carbon films APPLIED MATERIALS INC (US) 2007-03-14 CN disclosed
CN-1662676-A Method for forming ultra low k films using electron beam APPLIED MATERIALS INC (US) 2005-08-31 CN disclosed
EP-0718281-B1 CYCLOHEXANEDIUREA DERIVATIVE AND PROCESS FOR PRODUCING THE SAME NISSIN FOOD PRODUCTS LTD (JP) 2001-06-27 EP disclosed
US-5733931-A ANTICHOLESTEROL AGENTS NISSIN FOOD PRODUCTS CO., LTD. (JP) 1998-03-31 US disclosed
EP-0718281-A1 CYCLOHEXANEDIUREA DERIVATIVE AND PROCESS FOR PRODUCING THE SAME NISSIN FOOD PRODUCTS CO., LTD. (JP) 1996-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES HDHD5, NAAA, BROX ALDH1A1 3801/4885MAPT 388/4885POLB 3555/4885
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ALDH1A1 2743/4885MAPT 695/4885POLB 4159/4885
US-20100324091-A1 Pyrazolone Derivative SERPINE1, SERPINC1, TFPI ALDH1A1 517/4885MAPT 2810/4885POLB 3756/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 ALDH1A1 4326/4885MAPT 1422/4885POLB 2580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.