Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.53 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.53 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28456499 | 0.85 | CA1 (0.67) | CA1CA2CA9CA5ALMNA | |
| SCHEMBL9440624 | 0.84 | CA9 (0.42) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL2470421 | 0.83 | CA1 (0.56) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL9293241 | 0.82 | CA1 (0.54) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL29200455 | 0.82 | CA1 (0.54) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL29200471 | 0.82 | CA1 (0.54) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL29200461 | 0.82 | CA1 (0.54) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL29200465 | 0.82 | CA1 (0.54) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL7339510 | 0.82 | CA2 (0.73) | CA1CA2CA9CA5ACA12 | |
| Lithium Ion SCHEMBL11258643 | 0.81 | CA1 (0.67) | CA1CA2CA9CA5ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56110722-A | — | — | None | — | — | JP | disclosed |
| CN-117683336-B | Bamboo charcoal biodegradable conductive composite material and preparation method thereof | 国际竹藤中心 | 2024-04-23 | — | — | CN | disclosed |
| CN-117683336-A | Bamboo charcoal biodegradable conductive composite material and preparation method thereof | 国际竹藤中心 | 2024-03-12 | — | — | CN | disclosed |
| US-5300332-A | Modified with an aromatic sulfonic acid compound; tensile strength | POLYPLASTICS CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| EP-0556050-A1 | Modified polyester and method of manufacturing same | POLYPLASTICS CO. LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |
| JP-S56110722-A | PREPARATION OF POLYESTER WITH EXCELLENT PARTICLE DISPERSIBILITY | TORAY IND INC | 1981-09-02 | — | — | JP | disclosed |