Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301986 | 0.89 | CYP2D6 (0.46) | ALDH1A1HSD11B1UBE2MDCUN1D1MEN1 | |
| SCHEMBL9301405 | 0.87 | ACHE (0.46) | KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL9301293 | 0.86 | LMNA (0.46) | ALDH1A1HSD11B1UBE2MDCUN1D1MEN1 | |
| SCHEMBL9302303 | 0.86 | EPHX2 (0.47) | HPGDKDM4EALDH1A1HSD11B1UBE2M | |
| SCHEMBL9301620 | 0.83 | RBP4 (0.48) | HPGDALDH1A1HSD11B1UBE2MDCUN1D1 | |
| SCHEMBL9302654 | 0.80 | EPHX2 (0.45) | TSHRPKMKDM4EALDH1A1GAA | |
| SCHEMBL9301815 | 0.75 | ADRA1D (0.63) | — | |
| SCHEMBL9302183 | 0.73 | CYP2D6 (0.44) | ALDH1A1HSD11B1UBE2MDCUN1D1MEN1 | |
| SCHEMBL9302070 | 0.72 | EPHX2 (0.47) | HPGDKDM4EALDH1A1HSD11B1UBE2M | |
| SCHEMBL9302730 | 0.72 | EPHX2 (0.51) | HPGDKDM4EALDH1A1HSD11B1UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |