Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302303 | 0.87 | EPHX2 (0.47) | LMNAHPGDHSD11B1MGLLMEN1 | |
| SCHEMBL9301405 | 0.87 | ACHE (0.46) | LMNAPOLBKMT2AALDH1A1 | |
| SCHEMBL9301986 | 0.86 | CYP2D6 (0.46) | POLBHSD11B1MGLLMEN1KMT2A | |
| SCHEMBL9301807 | 0.83 | TSHR (0.45) | HPGDHSD11B1MEN1KMT2AUBE2M | |
| SCHEMBL9301293 | 0.82 | LMNA (0.46) | LMNAHSD11B1MGLLMEN1KMT2A | |
| SCHEMBL9302778 | 0.80 | SIGMAR1 (0.46) | LMNAUBE2MDCUN1D1ALDH1A1 | |
| SCHEMBL9302654 | 0.79 | EPHX2 (0.45) | LMNAHSD11B1MGLLMEN1KMT2A | |
| SCHEMBL9301625 | 0.76 | ADRA1D (0.54) | RBP4LMNAPOLBHPGDHSD11B1 | |
| SCHEMBL13503927 | 0.75 | LMNA (0.65) | RBP4LMNAPOLBHPGDHSD11B1 | |
| SCHEMBL9302070 | 0.74 | EPHX2 (0.47) | LMNAHPGDHSD11B1MGLLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |