Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIMP2 | Q13155 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 10/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301121 | 0.89 | ACHE (0.45) | AIMP2MAPTSIGMAR1MAPK1LTA4H | |
| SCHEMBL9301593 | 0.87 | SIGMAR1 (0.48) | MAPTKDM4EALDH1A1SIGMAR1LTA4H | |
| SCHEMBL9303117 | 0.86 | LTA4H (0.48) | MAPTMAPK1LTA4H | |
| SCHEMBL9302778 | 0.86 | SIGMAR1 (0.46) | MAPTKDM4EALDH1A1GAASIGMAR1 | |
| SCHEMBL9302452 | 0.84 | KDM4E (0.44) | AIMP2MAPTKDM4EALDH1A1GLA | |
| SCHEMBL9300946 | 0.83 | NPC1 (0.52) | KDM4EALDH1A1SIGMAR1LTA4H | |
| SCHEMBL9301653 | 0.80 | ACHE (0.47) | MAPTALDH1A1SIGMAR1MAPK1LTA4H | |
| SCHEMBL9301986 | 0.79 | CYP2D6 (0.46) | ALDH1A1L3MBTL1 | |
| SCHEMBL9302321 | 0.79 | ATM (0.42) | MAPTKDM4EALDH1A1ATMSIGMAR1 | |
| SCHEMBL9301861 | 0.75 | BACE1 (0.49) | ALDH1A1CXCR4DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |