Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301593 | 0.87 | SIGMAR1 (0.48) | LTA4HALDH1A1KDM4ESIGMAR1HTR2B | |
| SCHEMBL9303117 | 0.84 | LTA4H (0.48) | LTA4H | |
| SCHEMBL9301121 | 0.83 | ACHE (0.45) | BCHEACHELTA4HSIGMAR1 | |
| SCHEMBL9302817 | 0.83 | AIMP2 (0.53) | LTA4HALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL9302778 | 0.80 | SIGMAR1 (0.46) | LTA4HALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL9301653 | 0.78 | ACHE (0.47) | NPC1ACHELTA4HALDH1A1KMT2A | |
| SCHEMBL9302321 | 0.77 | ATM (0.42) | LTA4HALDH1A1KDM4EKMT2ASIGMAR1 | |
| SCHEMBL9300949 | 0.76 | ADRA1D (0.66) | ACHEALDH1A1POLB | |
| SCHEMBL9302546 | 0.72 | SIGMAR1 (0.46) | ALDH1A1KDM4ESIGMAR1POLBHTR2B | |
| SCHEMBL9302549 | 0.70 | LMNA (0.43) | NPC1ALDH1A1KDM4EKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |