Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301121 | 0.87 | ACHE (0.45) | SIGMAR1MAPTDRD4LTA4HHTR1A | |
| SCHEMBL9300946 | 0.87 | NPC1 (0.52) | SIGMAR1KDM4EALDH1A1LTA4HHTR2B | |
| SCHEMBL9302817 | 0.87 | AIMP2 (0.53) | SIGMAR1KDM4EALDH1A1MAPTDRD4 | |
| SCHEMBL9302546 | 0.84 | SIGMAR1 (0.46) | SIGMAR1KDM4EALDH1A1MAPTMCHR1 | |
| SCHEMBL9302778 | 0.84 | SIGMAR1 (0.46) | SIGMAR1KDM4EALDH1A1MAPTDRD4 | |
| SCHEMBL9303117 | 0.82 | LTA4H (0.48) | MAPTLTA4H | |
| SCHEMBL9301653 | 0.78 | ACHE (0.47) | SIGMAR1ALDH1A1MAPTLTA4HHTR1A | |
| SCHEMBL9302321 | 0.77 | ATM (0.42) | SIGMAR1KDM4EALDH1A1MAPTLTA4H | |
| SCHEMBL9301600 | 0.76 | ADRA1D (0.74) | ALDH1A1DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL9301861 | 0.74 | BACE1 (0.49) | ALDH1A1DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |