Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22263574 | 0.86 | ALOX5 (0.63) | L3MBTL1ALOX5LMNA | |
| SCHEMBL822636 | 0.85 | TSHR (0.51) | TSHRCES2CES1AKR1B1CNR2 | |
| SCHEMBL5593472 | 0.85 | TSHR (0.47) | TSHRCES2CES1AKR1B1CNR2 | |
| SCHEMBL559690 | 0.85 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBKMT2ALMNA | |
| SCHEMBL2586905 | 0.84 | TSHR (0.53) | TSHRCES2CES1AKR1B1CNR2 | |
| SCHEMBL27700031 | 0.84 | TSHR (0.46) | TSHRCES2CES1AKR1B1CNR2 | |
| SCHEMBL15309537 | 0.84 | ALDH1A1 (0.53) | TSHRL3MBTL1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL10050755 | 0.83 | CA2 (0.48) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL558881 | 0.83 | KMT2A (0.47) | CNR2L3MBTL1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL5578486 | 0.81 | CES2 (0.55) | TSHRCES2CES1AKR1B1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611900-B | Imidazole pyrazinone fluorescein and preparation method thereof | 中国科学院深圳先进技术研究院 | 2024-04-26 | — | — | CN | claimed |
| US-10202584-B2 | Red-shifted luciferase-luciferin pairs for enhanced bioluminescence | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-02-12 | — | — | US | claimed |
| US-20180057801-A1 | RED-SHIFTED LUCIFERASE-LUCIFERIN PAIRS FOR ENHANCED BIOLUMINESCENCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-03-01 | — | — | US | claimed |
| US-20260077068-A1 | ATP-INDEPENDENT BIOLUMINESCENT REPORTER VARIANTS TO IMPROVE IN VIVO IMAGING | UNIV VIRGINIA PATENT FOUNDATION (US) | 2026-03-19 | — | — | US | disclosed |
| US-20260016473-A1 | REAGENT FOR DETECTING SARS-RELATED CORONAVIRUS | AIST (JP) | 2026-01-15 | — | — | US | disclosed |
| WO-2025084165-A1 | METHOD FOR EVALUATING DENATURED STATE OF ANTIBODY | 国立研究開発法人産業技術総合研究所 | 2025-04-24 | — | — | WO | disclosed |
| WO-2024262411-A1 | SERUM ALBUMIN DETECTION AGENT | 国立研究開発法人産業技術総合研究所 | 2024-12-26 | — | — | WO | disclosed |
| CN-115611900-B | Imidazole pyrazinone fluorescein and preparation method thereof | 中国科学院深圳先进技术研究院 | 2024-04-26 | — | — | CN | disclosed |
| WO-2024014536-A1 | REAGENT FOR DETECTING SARS-RELATED CORONAVIRUS | 国立研究開発法人産業技術総合研究所 | 2024-01-18 | — | — | WO | disclosed |
| WO-2024014536-A1 | REAGENT FOR DETECTING SARS-RELATED CORONAVIRUS | 国立研究開発法人産業技術総合研究所 | 2024-01-18 | — | — | WO | disclosed |
| US-20230288338-A1 | LUMINESCENT SUBSTRATE COMPOUND | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2023-09-14 | — | — | US | disclosed |
| US-7638513-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2009-12-29 | — | — | US | disclosed |
| WO-2009099636-A1 | CONJUGATION OF SMALL MOLECULES TO OCTAARGININE TRANSPORTERS FOR OVERCOMING MULTI-DRUG RESISTANCE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2009-08-13 | — | — | WO | disclosed |
| US-20090136974-A1 | Luciferin Luminescent Substrate of Marine Ostracod Crustacean and Method for Production Thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE TECHNOLOGY (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20090136974-A1 | Luciferin Luminescent Substrate of Marine Ostracod Crustacean and Method for Production Thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE TECHNOLOGY (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20090075309-A1 | Bisdeoxycoelenterazine derivatives, methods of use, and BRET2 systems | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-03-19 | — | — | US | disclosed |
| US-20070167426-A1 | Compounds for the treatment of inflammatory disorders and microbial diseases | SCHERING CORPORATION | 2007-07-19 | — | — | US | disclosed |
| US-20070167426-A1 | Compounds for the treatment of inflammatory disorders and microbial diseases | SCHERING CORPORATION | 2007-07-19 | — | — | US | disclosed |
| US-20060178366-A1 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION | 2006-08-10 | — | — | US | disclosed |
| US-20060178366-A1 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167426-A1 | Compounds for the treatment of inflammatory disorders and microbial diseases | MMP12, ADAMTS1, ADAM33 | TSHR 4043/4885CES2 698/4885CES1 228/4885 |
| US-20090136974-A1 | Luciferin Luminescent Substrate of Marine Ostracod Crustacean and Method for Production Thereof | GLB1, DCXR, GALR1 | TSHR 1113/4885CES2 760/4885CES1 192/4885 |
| US-20260077068-A1 | ATP-INDEPENDENT BIOLUMINESCENT REPORTER VARIANTS TO IMPROVE IN VIVO IMAGING | KCNN2, KCNN1, ATP1B2 | TSHR 3056/4885CES2 1698/4885CES1 2518/4885 |
| US-20060178366-A1 | Compounds for the treatment of inflammatory disorders | MMP12, ADAMTS1, TNF | TSHR 3764/4885CES2 893/4885CES1 262/4885 |
| US-20230288338-A1 | LUMINESCENT SUBSTRATE COMPOUND | MRPL21, FAM162A, TALDO1 | TSHR 4577/4885CES2 3301/4885CES1 2398/4885 |
| US-20180057801-A1 | RED-SHIFTED LUCIFERASE-LUCIFERIN PAIRS FOR ENHANCED BIOLUMINESCENCE | LUC7L2, SCLY, GLB1 | TSHR 1968/4885CES2 260/4885CES1 901/4885 |
| US-10202584-B2 | Red-shifted luciferase-luciferin pairs for enhanced bioluminescence | LUC7L2, SCLY, GLB1 | TSHR 1968/4885CES2 260/4885CES1 901/4885 |
| US-20090075309-A1 | Bisdeoxycoelenterazine derivatives, methods of use, and BRET2 systems | GSTA2, BCHE, COMT | TSHR 2389/4885CES2 4/4885CES1 407/4885 |
| US-20260016473-A1 | REAGENT FOR DETECTING SARS-RELATED CORONAVIRUS | SARS1, CYP2F1, CYP7A1 | TSHR 1882/4885CES2 82/4885CES1 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.