Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL5087538 | 0.97 | PPARG (0.41) | PPARGHTTALDH1A1LMNANFE2L2 | |
| SCHEMBL28298872 | 0.89 | PPARG (0.45) | PPARGHTTALDH1A1LMNANFE2L2 | |
| Methacrylic Acid SCHEMBL38651194 | 0.87 | TDP1 (0.44) | PPARGHTTALDH1A1LMNANFE2L2 | |
| Methacrylic Acid SCHEMBL7732677 | 0.85 | GLA (0.43) | PPARGHTTALDH1A1LMNANFE2L2 | |
| Methacrylic Acid SCHEMBL7729849 | 0.84 | HTT (0.42) | PPARGHTTALDH1A1LMNANFE2L2 | |
| (Z)-1,2-Diphenylethene SCHEMBL5875859 | 0.83 | ALDH1A1 (0.56) | HTTALDH1A1LMNAGLATDP1 | |
| (Z)-1,2-Diphenylethene SCHEMBL5875864 | 0.83 | ALDH1A1 (0.56) | HTTALDH1A1LMNAGLATDP1 | |
| SCHEMBL27968511 | 0.83 | PPARG (0.38) | PPARGHTTALDH1A1LMNANFE2L2 | |
| SCHEMBL10491653 | 0.82 | PPARG (0.37) | PPARGHTTALDH1A1LMNANFE2L2 | |
| SCHEMBL10491730 | 0.82 | PPARG (0.37) | PPARGHTTALDH1A1LMNANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108700580-A | The detection method of additive, surface conditioning agent, surface modified latex particle, the manufacturing method of surface modified latex particle, latex agglutination reaction reagent, kit and target substance | JSR株式会社 | 2018-10-23 | — | — | CN | disclosed |
| EP-0288059-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1994-02-23 | — | — | EP | disclosed |
| US-5153115-A | A backing or subbing antistatic layer comprising an acrylic ester, amide or ketone having ether, amine and/or sulfide groups; high-speed, automatic development protection | FUJI PHOTO FILM CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0401826-A1 | Silver halide photographic materials and method for manufacture thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4943520-A | SUBBING LAYER OF POLYOLS; ENDCAPPED POLYETHERS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-07-24 | — | — | US | disclosed |