SCHEMBL940065

SCHEMBL940065

NNC(=O)NCC1CCC(C(=O)O)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLG P00747 1/20 0.52
PLAT P00750 1/20 0.52
LMNA P02545 1/20 0.52
TDP1 Q9NUW8 1/20 0.48
KMT2A Q03164 4/20 0.43
ANPEP P15144 1/20 0.42
ENPEP Q07075 1/20 0.42
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 1/20 0.41
EPHX1 P07099 3/20 0.41
MEN1 O00255 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2D6 P10635 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
VCP P55072 2/20 0.38
GAA P10253 2/20 0.37
GFER P55789 1/20 0.37
KDM4E B2RXH2 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7430073 1.00 PLG (0.52) PLGPLATLMNATDP1KMT2A
Trifluoroacetic Acid SCHEMBL7418767 0.91 PLG (0.43) PLGPLATLMNATDP1KMT2A
Trifluoroacetic Acid SCHEMBL939948 0.91 PLG (0.43) PLGPLATLMNATDP1KMT2A
SCHEMBL31270861 0.88
SCHEMBL8596237 0.81 TDP1 (0.76) PLGPLATLMNATDP1KMT2A
SCHEMBL8596242 0.81 TDP1 (0.76) PLGPLATLMNATDP1KMT2A
SCHEMBL8595498 0.80 KMT2A (0.46) PLGPLATLMNATDP1KMT2A
SCHEMBL8595695 0.80 KMT2A (0.46) PLGPLATLMNATDP1KMT2A
SCHEMBL4040744 0.79 EPHX1 (0.63) TDP1ALDH1A1CYP3A4EPHX1CYP2D6
SCHEMBL8601731 0.78 PLG (0.57) PLGPLATLMNATDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-07-31 US disclosed
US-12269800-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2025-04-08 US disclosed
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-02-13 US disclosed
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2024-07-25 US disclosed
US-11999694-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2024-06-04 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
WO-2023076586-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. (US) 2023-05-04 WO disclosed
WO-2023076586-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. (US) 2023-05-04 WO disclosed
US-20160361295-A1 FURO[3, 2-B] PYRR0L-3-ONES AS CATHESPIN S INHIBITORS AMURA THERAPEUTICS LTD (GB) 2016-12-15 US disclosed
WO-2002057248-A2 INHIBITORS OF CRUZIPAIN AND OTHER CYSTEINE PROTEASES AMURA THERAPEUTICS LIMITED (GB) 2002-07-25 WO disclosed
WO-2002057249-A1 CYCLIC 2-CARBONYLAMINOKETONES AS INHIBITORS OF CRUZIPAIN AND OTHER CYSTEINE PROTEASES AMURA THERAPEUTICS LIMITED (GB) 2002-07-25 WO disclosed
WO-2002057270-A1 INHIBITORS OF CRUZIPAIN AND OTHER CYSTEINE PROTEASES AMURA THERAPEUTICS LIMITED (GB) 2002-07-25 WO disclosed
WO-2002057246-A2 INHIBITORS OF CRUZIPAIN AND OTHER CYSTEINE PROTEASES AMURA THERAPEUTICS LIMITED (GB) 2002-07-25 WO disclosed
US-6245743-B1 ADMINISTERING ARGININE-CONTAINING OLIGOPEPTIDE AS ANTICOAGULANT; CARDIOVASCULAR DISORDERS COR THERAPEUTICS, INC. 2001-06-12 US disclosed
US-6046169-A Inhibitors of factor XA COR THERAPEUTICS, INC. (US) 2000-04-04 US disclosed
US-5919765-A USING A (DI- OR TRI)PEPTIDES COR THERAPEUTICS, INC. (US) 1999-07-06 US disclosed
EP-0846125-A2 INHIBITORS OF FACTOR Xa COR THERAPEUTICS, INC. (US) 1998-06-10 EP disclosed
US-5721214-A PEPTIDE ANTICOAGULANTS COR THERAPEUTICS, INC. (US) 1998-02-24 US disclosed
WO-1996040743-A2 INHIBITORS OF FACTOR Xa COR THERAPEUTICS, INC. (US) 1996-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT PLG 917/4885PLAT 1281/4885LMNA 1333/4885
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT PLG 917/4885PLAT 1281/4885LMNA 1333/4885
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT PLG 917/4885PLAT 1281/4885LMNA 1333/4885
US-20160361295-A1 FURO[3, 2-B] PYRR0L-3-ONES AS CATHESPIN S INHIBITORS CTSS, CTSL, CTSK PLG 389/4885PLAT 186/4885LMNA 4057/4885
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT PLG 917/4885PLAT 1281/4885LMNA 1333/4885
US-12269800-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT PLG 917/4885PLAT 1281/4885LMNA 1333/4885
US-11999694-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT PLG 917/4885PLAT 1281/4885LMNA 1333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.