Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HEXA | P06865 | 1/20 | 0.38 |
| ▸ | HEXB | P07686 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23502019 | 0.75 | ALDH1A1 (0.44) | KMT2ASMN1; SMN2TDP1ALDH1A1LMNA | |
| SCHEMBL15210361 | 0.70 | LMNA (0.47) | KMT2ASMN1; SMN2TDP1ALDH1A1LMNA | |
| SCHEMBL24926817 | 0.68 | TGFBR1 (0.33) | KMT2ASMN1; SMN2TDP1ALDH1A1LMNA | |
| SCHEMBL15210427 | 0.68 | LMNA (0.68) | KMT2ASMN1; SMN2TDP1ALDH1A1LMNA | |
| SCHEMBL15210435 | 0.67 | TRPM8 (0.43) | KMT2ASMN1; SMN2TDP1ALDH1A1LMNA | |
| SCHEMBL28827806 | 0.62 | RAB9A (0.50) | KMT2ASMN1; SMN2TDP1ALDH1A1LMNA | |
| SCHEMBL28817004 | 0.61 | NPC1 (0.58) | KMT2ASMN1; SMN2ALDH1A1MEN1KDM4E | |
| SCHEMBL27285044 | 0.60 | TRPV3 (0.55) | KMT2ASMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL17066980 | 0.60 | TDP1 (0.41) | KMT2ASMN1; SMN2TDP1ALDH1A1LMNA | |
| SCHEMBL4691850 | 0.60 | PDE3B (0.47) | KMT2ASMN1; SMN2ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6192252-A | — | — | None | — | — | JP | disclosed |
| JP-H06192252-A | PYRAZINE DERIVATIVE AND HERBICIDE | NISSAN CHEM IND LTD | 1994-07-12 | — | — | JP | disclosed |