Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.47 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210090 | 0.81 | MAPT (0.50) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL7554768 | 0.80 | AKR1C3 (0.38) | ALDH1A1TSHR | |
| SCHEMBL2480621 | 0.79 | MAPT (0.47) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Lithium Ion SCHEMBL29248324 | 0.78 | ALDH1A1 (0.37) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL18492569 | 0.75 | FBP1 (0.42) | ALDH1A1CYP2C9TSHR | |
| SCHEMBL18492573 | 0.75 | FBP1 (0.42) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL3673702 | 0.75 | MAOB (0.53) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL3671132 | 0.75 | CYP1B1 (0.53) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL3671136 | 0.75 | CYP1B1 (0.53) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL3673698 | 0.75 | MAOB (0.53) | HDAC3HDAC4HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111944247-A | Preparation method of uniform silicon dioxide microspheres | 无锡迈科为生物科技有限公司 | 2020-11-17 | — | — | CN | claimed |
| CN-111944247-A | Preparation method of uniform silicon dioxide microspheres | 无锡迈科为生物科技有限公司 | 2020-11-17 | — | — | CN | disclosed |
| EP-1777764-B1 | GELLING AGENT FOR ALKALINE BATTERY AND ALKALINE BATTERY | SANYO CHEMICAL IND LTD (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-7866806-B2 | Liquid-composition set, and liquid-applying method and liquid-applying apparatus employing the set | CANON KABUSHIKI KAISHA (JP) | 2011-01-11 | — | — | US | disclosed |
| US-7838156-B2 | Thickener for alkaline battery and alkaline battery | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2010-11-23 | — | — | US | disclosed |
| EP-1798791-B1 | THICKENER FOR ALKALINE BATTERY AND ALKALINE BATTERY | SANYO CHEMICAL IND LTD (JP) | 2010-11-03 | — | — | EP | disclosed |
| US-7579115-B2 | mixing gelling agent crosslinked poly(meth)acrylate(salt), an alkaline electrolyte (e.g. a high-concentration aqueous solution of potassium hydroxide, contains zinc powder) so as to prepare a gelling agent for use in an alkaline battery having a gel-form negative electrode; impact resistance | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2009-08-25 | — | — | US | disclosed |
| US-7303818-B2 | Electrophoretic particles, electrophoretic dispersion liquid, and electrophoretic display device | CANON KABUSIHI KAISHA (JP) | 2007-12-04 | — | — | US | disclosed |
| US-20070259269-A1 | long term retention of discharge characteristics and improved impact resistance; zinc powder, potassium hydroxide; mixture of a crosslinked acrylic polymer with crosslinking agent that is hydrolytically decomposable (ester) and a crosslinked polymer with crosslinking agent that is nonhydrolyzable (allyl) | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2007-11-08 | — | — | US | disclosed |
| US-20070231703-A1 | mixing gelling agent crosslinked poly(meth)acrylate(salt), an alkaline electrolyte (e.g. a high-concentration aqueous solution of potassium hydroxide, contains zinc powder) so as to prepare a gelling agent for use in an alkaline battery having a gel-form negative electrode; impact resistance | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1798791-A1 | THICKENER FOR ALKALINE BATTERY AND ALKALINE BATTERY | Sanyo Chemical Industries, Ltd. (JP) | 2007-06-20 | — | — | EP | disclosed |
| EP-1777764-A1 | GELLING AGENT FOR ALKALINE BATTERY AND ALKALINE BATTERY | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2007-04-25 | — | — | EP | disclosed |
| US-20060146087-A1 | Liquid, ph-sensitive ink, method and apparatus using the same | CANON KABUSHIKI KAISHA (JP) | 2006-07-06 | — | — | US | disclosed |
| US-20050227155-A1 | Electrophoretic particles, electrophoretic dispersion liquid, and electrophoretic display device | CANON KABUSHIKI KAISHA (JP) | 2005-10-13 | — | — | US | disclosed |
| WO-2004106440-A1 | LIQUID, PH-SENSITIVE INK, METHOD AND APPARATUS USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2004-12-09 | — | — | WO | disclosed |
| US-6667133-B1 | Cross-linked polymer of (meth)acrylic acid and/or its alkali metal salt, water swelling particle | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2003-12-23 | — | — | US | disclosed |
| EP-0432946-B1 | Charge control resin particles for an electrophotographic toner and a method of manufacturing the same | MITA INDUSTRIAL CO LTD (JP) | 1997-04-23 | — | — | EP | disclosed |
| EP-0432946-A1 | Charge control resin particles and a method of manufacturing the same | MITA INDUSTRIAL CO., LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |