Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | MMP12 | P39900 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | MMP14 | P50281 | 2/20 | 0.45 |
| ▸ | MMP16 | P51512 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2947086 | 0.91 | PTGS2 (0.49) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL9452111 | 0.81 | PGR (0.49) | PGRMMP2MMP9MMP8MMP12 | |
| SCHEMBL9793435 | 0.80 | HTR6 (0.48) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL5161585 | 0.79 | PTGS2 (0.54) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL5086111 | 0.76 | HSD11B1 (0.51) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL9462475 | 0.76 | RAPGEF4 (0.41) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL9462782 | 0.76 | MMP1 (0.42) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL7871344 | 0.76 | PTGS2 (0.49) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL7871346 | 0.76 | PTGS2 (0.56) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL10396332 | 0.76 | HSD11B1 (0.57) | PGRMMP2MMP9MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532965-A2 | Process for the preparation of aromatic carbonyl- or sulfonyl compounds with aryletherstructure | BASF Aktiengesellschaft (DE) | 1993-03-24 | — | — | EP | disclosed |