Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 9/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503481 | 0.75 | AGTR2 (0.40) | BCHE | |
| SCHEMBL9503474 | 0.74 | NPC1 (0.40) | SIGMAR1 | |
| SCHEMBL9442784 | 0.71 | ALDH1A1 (0.49) | NPSR1 | |
| SCHEMBL9503470 | 0.70 | CA1 (0.40) | — | |
| SCHEMBL21091908 | 0.69 | KMT2A (0.51) | HTR1ASLC6A4 | |
| SCHEMBL21091907 | 0.69 | KMT2A (0.51) | HTR1ASLC6A4 | |
| SCHEMBL9504640 | 0.68 | PTGER4 (0.37) | — | |
| SCHEMBL11214829 | 0.68 | BCHE (0.44) | BCHE | |
| SCHEMBL9814112 | 0.68 | MAOA (0.45) | BCHEHTR1ASIGMAR1 | |
| SCHEMBL9504636 | 0.67 | TAOK1 (0.38) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321968-B1 | COMPOUNDS ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1993-07-28 | — | — | EP | disclosed |
| US-5151414-A | Hypotensive agents | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1992-09-29 | — | — | US | disclosed |
| US-5070106-A | HYPOTENSIVES, CEREBRAL DISORDERS | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1991-12-03 | — | — | US | disclosed |
| EP-0321968-A2 | Compounds active on the cardiovascular system | ZAMBON GROUP S.p.A. (IT) | 1989-06-28 | — | — | EP | disclosed |