Sugi Predict

Sugi Predict / Compounds / SCHEMBL955708

SCHEMBL955708

SCHEMBL955708

CC(=O)NCc1cccc(B(O)O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 2/20 0.53
▸ LPL P06858 2/20 0.49
▸ LIPG Q9Y5X9 2/20 0.49
▸ PSMB5 P28074 6/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.46
▸ KIF11 P52732 1/20 0.45
▸ HDAC3 O15379 1/20 0.45
▸ HDAC4 P56524 1/20 0.45
▸ HDAC1 Q13547 1/20 0.45
▸ HDAC7 Q8WUI4 1/20 0.45
▸ HDAC2 Q92769 1/20 0.45
▸ HDAC10 Q969S8 1/20 0.45
▸ HDAC11 Q96DB2 1/20 0.45
▸ HDAC8 Q9BY41 1/20 0.45
▸ HDAC6 Q9UBN7 1/20 0.45
▸ HDAC9 Q9UKV0 1/20 0.45
▸ HDAC5 Q9UQL6 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ CXCR1 P25024 1/20 0.43
▸ CXCR2 P25025 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5237478 0.84 LPL (0.54) ENPP2LPLLIPG
SCHEMBL1899410 0.84 NPSR1 (0.57) NPSR1KIF11HDAC3HDAC4HDAC1
SCHEMBL14830589 0.83 TRPV1 (0.53) LIPGHDAC3HDAC4HDAC1HDAC2
SCHEMBL16634483 0.80 TGM2 (0.50) ENPP2LPLLIPGPSMB5CXCR1
SCHEMBL885310 0.79 SRC (0.56) —
SCHEMBL30006359 0.79 SRC (0.56) —
SCHEMBL1162968 0.79 GLS (0.49) ENPP2PSMB5HDAC1PSMB8
SCHEMBL3724201 0.79 ENPP2 (0.60) ENPP2LPLLIPG
SCHEMBL101621 0.79 KMT2A (0.59) LPLLIPGHDAC3HDAC1HDAC2
SCHEMBL3031683 0.78 ALDH1A1 (0.55) ENPP2PSMB5NPSR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210790-A1 GEL FOR USE IN GASTROINTESTINAL ENDOSCOPY AND ENDODERMAL, EPIDERMAL, AND OTHER MUCOSAL USES THE JOHNS HOPKINS UNIVERSTY 2023-07-06 — — US claimed
EP-4157998-A1 GEL FOR USE IN GASTROINTESTINAL ENDOSCOPY AND ENDODERMAL, EPIDERMAL, AND OTHER MUCOSAL USES The Johns Hopkins University (US) 2023-04-05 — — EP claimed
CN-114794335-A Novel method for processing blackberry pulp 浙江量品生物科技有限公司 2022-07-29 — — CN claimed
EP-3344232-B1 MICELLES FOR MUCOADHESIVE DRUG DELIVERY UNIV MCMASTER (CA) 2022-01-26 — — EP claimed
US-10611908-B2 Micelles for mucoadhesive drug delivery MCMASTER UNIVERSITY (CA) 2020-04-07 — — US claimed
US-20180265694-A1 Micelles for Mucoadhesive Drug Delivery MCMASTER UNIVERSITY (CA) 2018-09-20 — — US claimed
EP-3344232-A1 MICELLES FOR MUCOADHESIVE DRUG DELIVERY Mcmaster University (CA) 2018-07-11 — — EP claimed
WO-2017035656-A1 MICELLES FOR MUCOADHESIVE DRUG DELIVERY MCMASTER UNIVERSITY (CA) 2017-03-09 — — WO claimed
WO-2025235957-A1 P53 MUTANT STABILIZER AND USES THEREOF FRONTIER MEDICINES CORPORATION (US) 2025-11-13 — — WO disclosed
US-20230210790-A1 GEL FOR USE IN GASTROINTESTINAL ENDOSCOPY AND ENDODERMAL, EPIDERMAL, AND OTHER MUCOSAL USES THE JOHNS HOPKINS UNIVERSTY 2023-07-06 — — US disclosed
US-20230139250-A1 FORMULATIONS OF TIE-2 ACTIVATORS AND METHODS OF USE THEREOF EYEPOINT PHARMACEUTICALS INC (US) 2023-05-04 — — US disclosed
EP-4157998-A1 GEL FOR USE IN GASTROINTESTINAL ENDOSCOPY AND ENDODERMAL, EPIDERMAL, AND OTHER MUCOSAL USES The Johns Hopkins University (US) 2023-04-05 — — EP disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 — — US disclosed
US-11413242-B2 Formulations of Tie-2 activators and methods of use thereof EyePoint Pharmaceuticals, Inc. (US) 2022-08-16 — — US disclosed
US-20070232632-A1 Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs BAYER INTELLECTUAL PROPERTY GMBH (DE) 2007-10-04 — — US disclosed
US-7268130-B2 Benzothiadiazine compounds LES LABORATOIRES SERVIER (FR) 2007-09-11 — — US disclosed
EP-1812439-A2 KINASE INHIBITORS Takeda San Diego, Inc. (US) 2007-08-01 — — EP disclosed
US-20060094712-A1 New benzothiadiazine compounds LES LABORATOIRES SERVIER (FR) 2006-05-04 — — US disclosed
WO-2006044687-A2 KINASE INHIBITORS TAKEDA SAN DIEGO, INC. (US) 2006-04-27 — — WO disclosed
US-20060084650-A1 Kinase inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060084650-A1 Kinase inhibitors MAP3K20, MAP3K19, MAP3K1 ENPP2 1660/4885LPL 1857/4885LIPG 837/4885
US-11413242-B2 Formulations of Tie-2 activators and methods of use thereof TIE1, TEK, KDR ENPP2 50/4885LPL 826/4885LIPG 51/4885
US-20060094712-A1 New benzothiadiazine compounds SLC1A1, SLC1A2, GABRA5 ENPP2 1094/4885LPL 4630/4885LIPG 4471/4885
US-20230139250-A1 FORMULATIONS OF TIE-2 ACTIVATORS AND METHODS OF USE THEREOF TIE1, TEK, KDR ENPP2 50/4885LPL 826/4885LIPG 51/4885
US-20230210790-A1 GEL FOR USE IN GASTROINTESTINAL ENDOSCOPY AND ENDODERMAL, EPIDERMAL, AND OTHER MUCOSAL USES EPX, EPCAM, ELANE ENPP2 128/4885LPL 606/4885LIPG 25/4885
US-20070232632-A1 Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs TYMS, DPYD, DHFR ENPP2 1871/4885LPL 4629/4885LIPG 4170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.