Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 9/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519673 | 0.86 | NOS3 (0.41) | NOS3NOS1NOS2LNPEPKDM4E | |
| Hydrochloric Acid SCHEMBL9515348 | 0.83 | NOS3 (0.40) | NOS3NOS1NOS2LNPEPKDM4E | |
| SCHEMBL26802314 | 0.81 | MTNR1A (0.39) | NOS3NOS1NOS2LNPEPKDM4E | |
| SCHEMBL9566834 | 0.80 | LOXL2 (0.41) | — | |
| SCHEMBL26804290 | 0.79 | NOS1 (0.36) | NOS3NOS1NOS2LNPEPKDM4E | |
| SCHEMBL9566818 | 0.78 | ALDH1A1 (0.44) | LNPEPKDM4EMEN1KMT2A | |
| SCHEMBL9566774 | 0.78 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL2549948 | 0.78 | CCR1 (0.57) | NOS3NOS1NOS2KDM5BKDM4E | |
| SCHEMBL3307860 | 0.78 | NOS2 (0.62) | NOS3NOS1NOS2KDM4EMAPT | |
| SCHEMBL9568958 | 0.77 | AAK1 (0.38) | NOS3NOS1NOS2KDM4EACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |