Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 6/20 | 0.49 |
| ▸ | DRD3 | P35462 | 5/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602079 | 0.92 | SLC6A9 (0.55) | SLC6A9DRD2DRD3SIGMAR1SLC6A3 | |
| SCHEMBL9601398 | 0.87 | DRD2 (0.50) | SLC6A9DRD2DRD3SIGMAR1SLC6A3 | |
| Oxalic Acid SCHEMBL9602668 | 0.84 | DRD3 (0.50) | SLC6A9DRD2DRD3SIGMAR1SLC6A3 | |
| SCHEMBL9601390 | 0.82 | DRD2 (0.48) | SLC6A9DRD2DRD3SIGMAR1SLC6A3 | |
| SCHEMBL9601882 | 0.82 | SIGMAR1 (0.56) | SLC6A9DRD2DRD3SIGMAR1SLC6A3 | |
| SCHEMBL9601079 | 0.80 | HSD11B1 (0.57) | SLC6A9DRD2DRD3SIGMAR1SLC6A3 | |
| Alcohol SCHEMBL9600777 | 0.80 | KMT2A (0.54) | SLC6A9DRD2DRD3SIGMAR1SLC6A3 | |
| SCHEMBL7794410 | 0.80 | LMNA (0.52) | SLC6A9DRD2DRD3SIGMAR1SLC6A3 | |
| SCHEMBL7767918 | 0.79 | LMNA (0.53) | SLC6A9DRD2DRD3SIGMAR1SLC6A3 | |
| SCHEMBL7794415 | 0.79 | DRD3 (0.53) | DRD2DRD3SIGMAR1SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308476-B1 | BISPHENYLALKYLPIPERAZINE DERIVATIVES, A METHOD OF THEIR PREPARATION AND A PHARMACEUTICAL PREPARATION | Kabi Pharmacia AB (SE) | 1993-02-03 | — | — | EP | disclosed |