Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19223903 | 0.98 | MAPT (0.44) | MAPTALDH1A1POLBCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL2207969 | 0.98 | MAPT (0.44) | MAPTALDH1A1POLBCYP3A4CYP2D6 | |
| SCHEMBL28143791 | 0.98 | MAPT (0.44) | MAPTALDH1A1POLBCYP3A4CYP2D6 | |
| SCHEMBL27485167 | 0.98 | MAPT (0.44) | MAPTALDH1A1POLBCYP3A4CYP2D6 | |
| SCHEMBL21416476 | 0.98 | MAPT (0.44) | MAPTALDH1A1POLBCYP3A4CYP2D6 | |
| SCHEMBL24919973 | 0.98 | MAPT (0.44) | MAPTALDH1A1POLBCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL572560 | 0.96 | ALDH1A1 (0.42) | MAPTALDH1A1POLBCYP3A4CYP2D6 | |
| Fluoride SCHEMBL29252743 | 0.96 | MAPT (0.42) | MAPTALDH1A1POLBCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL29252918 | 0.96 | ALDH1A1 (0.42) | MAPTALDH1A1POLBCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL27371328 | 0.96 | ALDH1A1 (0.42) | MAPTALDH1A1POLBCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230031406-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-02-02 | — | — | US | disclosed |
| US-20230024108-A1 | ADENOSINE A2A RECEPTOR ANTAGONISTS | TEON THERAPEUTICS INC (US) | 2023-01-26 | — | — | US | disclosed |
| US-11339144-B2 | Heteroaryl Rheb inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2022-05-24 | — | — | US | disclosed |
| US-20210238165-A1 | HETEROARYL RHEB INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2021-08-05 | — | — | US | disclosed |
| US-20200247815-A1 | PYRAZOLYL-CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2020-08-06 | — | — | US | disclosed |
| CN-110471134-A | Surface treatment liquid and optical film | SUMITOMO CHEMICAL CO | 2019-11-19 | — | — | CN | disclosed |
| CN-110325887-A | Optical laminate | 住友化学株式会社 | 2019-10-11 | — | — | CN | disclosed |
| US-10266560-B2 | Bile acid analogs as FXR/TGR5 agonists and methods of use thereof | ENANTA PHARMACEUTICALS, INC. (US) | 2019-04-23 | — | — | US | disclosed |
| US-20180162862-A1 | INHIBITORS OF BACTERIAL GLYCOSYL TRANSFERASES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-06-14 | — | — | US | disclosed |
| US-9988386-B2 | Compounds for treatment of diseases of abnormal angiogenesis or aberrant growth factors and uses thereof | Kata Pharmaceuticals, Inc. (US) | 2018-06-05 | — | — | US | disclosed |
| CN-106468795-B | Curved surface image display panel polarization plates | 住友化学株式会社 | 2018-01-30 | — | — | CN | disclosed |
| US-9783501-B2 | Substituted quinolines as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2017-10-10 | — | — | US | disclosed |
| US-9725436-B2 | Cytochrome P450 inhibitors and their method of use | CORTENDO AB (PUBL) (US) | 2017-08-08 | — | — | US | disclosed |
| CN-106569296-A | Polarizing plate | 住友化学株式会社 | 2017-04-19 | — | — | CN | disclosed |
| CN-106569297-A | Polarizing plate | 住友化学株式会社 | 2017-04-19 | — | — | CN | disclosed |
| CN-106468795-A | Curved surface image display panel polarization plates | 住友化学株式会社 | 2017-03-01 | — | — | CN | disclosed |
| US-9562038-B2 | Bifunctional molecules with antibody-recruiting and entry inhibitory activity against the human immunodeficiency virus | YALE UNIVERSITY (US) | 2017-02-07 | — | — | US | disclosed |
| EP-0470391-A1 | Use of pyridines as perfume or aroma ingredients | FIRMENICH SA (CH) | 1992-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230031406-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NLRP1, NLRP3, NOD1 | MAPT 2020/4885ALDH1A1 1972/4885POLB 4644/4885 |
| US-20210238165-A1 | HETEROARYL RHEB INHIBITORS AND USES THEREOF | RHEB, KRAS, NRAS | MAPT 4119/4885ALDH1A1 3621/4885POLB 286/4885 |
| US-10266560-B2 | Bile acid analogs as FXR/TGR5 agonists and methods of use thereof | GPBAR1, NR1H4, SLC10A1 | MAPT 2547/4885ALDH1A1 2623/4885POLB 4613/4885 |
| US-20180162862-A1 | INHIBITORS OF BACTERIAL GLYCOSYL TRANSFERASES | SI, UGGT1, ALPI | MAPT 260/4885ALDH1A1 592/4885POLB 929/4885 |
| US-20230024108-A1 | ADENOSINE A2A RECEPTOR ANTAGONISTS | ADORA2A, ADORA2B, ADORA3 | MAPT 4769/4885ALDH1A1 458/4885POLB 2793/4885 |
| US-20200247815-A1 | PYRAZOLYL-CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | MAPK1, MAPK11, MAPK14 | MAPT 3727/4885ALDH1A1 1717/4885POLB 3697/4885 |
| US-11339144-B2 | Heteroaryl Rheb inhibitors and uses thereof | RHEB, GDI2, KRAS | MAPT 2840/4885ALDH1A1 3277/4885POLB 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.