Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205683 | 0.78 | HTR1A (0.53) | HTR1AHTR2CPDE3BPDE3APGR | |
| SCHEMBL9685648 | 0.74 | CMA1 (0.56) | HTR1AHTR2CPDE3BPDE3APGR | |
| SCHEMBL9686038 | 0.74 | ALDH1A1 (0.51) | HTR1AHTR2CPDE3BPDE3APGR | |
| SCHEMBL9685633 | 0.73 | KIF11 (0.51) | HTR1AHTR2CPDE3BPDE3APGR | |
| SCHEMBL9686113 | 0.73 | PGR (0.50) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL7767398 | 0.73 | PDE3B (0.50) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL9204486 | 0.73 | MAPT (0.59) | HTR1AHTR2CPDE3BPDE3APGR | |
| SCHEMBL7765507 | 0.73 | PDE3B (0.50) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL9685616 | 0.72 | HTR1A (0.60) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL9685728 | 0.71 | PDE3B (0.69) | HTR1AHTR2CPDE3BPDE3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |