Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 6/20 | 0.40 |
| ▸ | USP19 | O94966 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686141 | 0.87 | — | — | |
| SCHEMBL9685451 | 0.85 | ADRA2A (0.57) | — | |
| SCHEMBL9686858 | 0.81 | HTR3A (0.55) | TSHRUSP19MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9686615 | 0.79 | ADRA1A (0.49) | — | |
| SCHEMBL9685229 | 0.79 | USP19 (0.51) | TSHRUSP19MEN1KMT2A | |
| SCHEMBL9684556 | 0.77 | LMNA (0.51) | TSHRMEN1KMT2A | |
| SCHEMBL2921304 | 0.71 | ALDH1A1 (0.60) | TSHR | |
| SCHEMBL8500248 | 0.70 | MAPT (0.53) | TSHRMEN1KMT2A | |
| SCHEMBL3949243 | 0.70 | TNF (0.64) | MEN1KMT2A | |
| SCHEMBL8810668 | 0.69 | LMNA (0.56) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62056488-A | — | — | None | — | — | JP | disclosed |
| EP-0188094-B1 | QUINAZOLINE DERIVATIVES AND ANTIHYPERTENSIVE PREPARATIONS CONTAINING SAME AS EFFECTIVE COMPONENTS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4734418-A | Quinazoline compounds and antihypertensives | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| JP-S6256488-A | QUINAZOLINE DERIVATIVE AND PHARMACEUTICAL USE | MITSUI PETROCHEM IND LTD | 1987-03-12 | — | — | JP | disclosed |
| EP-0188094-A2 | Quinazoline derivatives and antihypertensive preparations containing same as effective components | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |