Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687454 | 0.92 | MEN1 (0.39) | PDE2AKMT2AMEN1ALDH1A1 | |
| SCHEMBL9687392 | 0.88 | CYP1A2 (0.46) | TSHRSMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL9687941 | 0.83 | EZH2 (0.40) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9164713 | 0.83 | MMP13 (0.48) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9688033 | 0.80 | HTT (0.49) | TSHRPKMSMN1; SMN2KMT2ALMNA | |
| SCHEMBL9687409 | 0.78 | LMNA (0.43) | TSHRKMT2ALMNAMEN1 | |
| SCHEMBL9160957 | 0.78 | SMN1; SMN2 (0.33) | TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9687391 | 0.77 | HPGD (0.39) | TSHRPKMSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9686935 | 0.76 | CNR1 (0.47) | ALDH1A1 | |
| SCHEMBL9688037 | 0.75 | TSHR (0.49) | TSHRMAPK10SMN1; SMN2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |