Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714087 | 0.79 | MMP1 (0.41) | MMP2MMP9APPMMP1 | |
| SCHEMBL9714207 | 0.78 | MMP1 (0.48) | MMP2MMP9MMP1 | |
| SCHEMBL9714079 | 0.78 | ADAM17 (0.56) | MMP2MMP9MMP1 | |
| SCHEMBL9713827 | 0.74 | GRIK1 (0.39) | MMP9MMP1 | |
| SCHEMBL6942498 | 0.73 | CTSK (0.39) | CTSKECE1APPPSMB5CTSB | |
| SCHEMBL7308423 | 0.69 | MMP1 (0.44) | CTSKMMP2MMP9ECE1CTSB | |
| SCHEMBL7308429 | 0.69 | MMP1 (0.44) | CTSKMMP2MMP9ECE1CTSB | |
| SCHEMBL8872910 | 0.68 | ECE1 (0.52) | CTSKMMP2ECE1PSMB5CTSB | |
| SCHEMBL8872913 | 0.68 | ECE1 (0.52) | CTSKMMP2ECE1PSMB5CTSB | |
| SCHEMBL8601030 | 0.68 | ECE1 (0.49) | CTSKECE1PSMB5CTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497192-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | disclosed |