Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727691 | 0.89 | MTNR1B (0.42) | KDM1AHDAC6CYSLTR1NPC1RAB9A | |
| SCHEMBL5506271 | 0.89 | MAOA (0.41) | — | |
| SCHEMBL9727674 | 0.86 | LTB4R (0.38) | — | |
| SCHEMBL9727677 | 0.82 | PTGDR2 (0.38) | — | |
| SCHEMBL9727669 | 0.80 | MTNR1A (0.43) | — | |
| SCHEMBL5518490 | 0.80 | F2 (0.41) | — | |
| SCHEMBL9727458 | 0.79 | PTGER1 (0.47) | — | |
| SCHEMBL9727749 | 0.79 | MAOA (0.34) | CYSLTR1CYSLTR2 | |
| SCHEMBL14435039 | 0.78 | AKR1B1 (0.40) | — | |
| SCHEMBL9727765 | 0.75 | MTNR1B (0.39) | CYSLTR1NPC1RAB9AMAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091533-A | Treating allergies, cardiovascular disorders, inflammation | MERCK FROSST CANADA, INC. (CA) | 1992-02-25 | — | — | US | disclosed |