Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727677 | 0.77 | PTGDR2 (0.38) | TDP1L3MBTL1PTGDR2FFAR1PPARG | |
| SCHEMBL9727665 | 0.74 | L3MBTL1 (0.38) | L3MBTL1PTGDR2TAAR1 | |
| SCHEMBL5506271 | 0.69 | MAOA (0.41) | FFAR1MAOB | |
| SCHEMBL9727331 | 0.67 | MTNR1A (0.37) | MAOB | |
| SCHEMBL9727632 | 0.64 | DRD2 (0.39) | FFAR1PPARGPPARD | |
| SCHEMBL21331850 | 0.63 | GPR84 (0.61) | FFAR1PPARGPPARDMAOBTAAR1 | |
| SCHEMBL10459582 | 0.62 | MAOB (0.48) | MAOB | |
| SCHEMBL10459597 | 0.62 | MAOB (0.45) | PPARGPPARDMAOB | |
| SCHEMBL27739159 | 0.61 | MAOB (0.41) | MAOB | |
| SCHEMBL27491253 | 0.61 | SLC6A4 (0.46) | FFAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091533-A | Treating allergies, cardiovascular disorders, inflammation | MERCK FROSST CANADA, INC. (CA) | 1992-02-25 | — | — | US | disclosed |
| EP-0447189-A1 | 5-Hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA INC. (CA) | 1991-09-18 | — | — | EP | disclosed |