Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727464 | 0.85 | KDM4E (0.36) | L3MBTL1AKR1B1MEN1KMT2A | |
| SCHEMBL9727331 | 0.80 | MTNR1A (0.37) | AKR1B1PTGER1HIF1AMTNR1BPTGER4 | |
| SCHEMBL9727653 | 0.77 | ABCB1 (0.38) | PTGER1MTNR1BPTGER4PTGER3PTGER2 | |
| SCHEMBL9727668 | 0.74 | TDP1 (0.36) | L3MBTL1PTGDR2TAAR1 | |
| SCHEMBL9727633 | 0.68 | LTA4H (0.38) | AKR1B1PTGER1MTNR1BPTGER4PTGER3 | |
| SCHEMBL9727700 | 0.67 | MTNR1A (0.35) | L3MBTL1AKR1B1PTGER1MTNR1BPTGER4 | |
| SCHEMBL9727458 | 0.66 | PTGER1 (0.47) | PTGER1PTGER4PTGER3PTGER2NR4A2 | |
| SCHEMBL9727777 | 0.65 | AKR1B1 (0.35) | AKR1B1KMT2A | |
| SCHEMBL9727691 | 0.63 | MTNR1B (0.42) | MTNR1BMEN1KMT2A | |
| SCHEMBL8677570 | 0.62 | PTGER1 (0.57) | PTGER1MTNR1BMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091533-A | Treating allergies, cardiovascular disorders, inflammation | MERCK FROSST CANADA, INC. (CA) | 1992-02-25 | — | — | US | disclosed |
| EP-0447189-A1 | 5-Hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA INC. (CA) | 1991-09-18 | — | — | EP | disclosed |