Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736020 | 0.90 | L3MBTL1 (0.49) | POLBHSD11B1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL9734732 | 0.82 | PKM (0.40) | KAT8L3MBTL1GRM5PKM | |
| SCHEMBL9734839 | 0.79 | CA1 (0.50) | KAT8GRM5KDM4EALDH1A1PKM | |
| SCHEMBL2524154 | 0.75 | L3MBTL1 (0.52) | TSHRL3MBTL1GRM5PKM | |
| SCHEMBL9867413 | 0.75 | TRPV3 (0.46) | POLBTSHRKAT8L3MBTL1HPGD | |
| SCHEMBL9735650 | 0.74 | HSD11B1 (0.43) | POLBHSD11B1TSHRALDH1A1PKM | |
| SCHEMBL30440671 | 0.74 | HRH4 (0.49) | TSHRHPGDGRM5KDM4EALDH1A1 | |
| SCHEMBL17869373 | 0.74 | HRH4 (0.49) | TSHRHPGDGRM5KDM4EALDH1A1 | |
| SCHEMBL9866569 | 0.74 | AR (0.51) | POLBKAT8HPGD | |
| SCHEMBL9865486 | 0.74 | KMT2A (0.43) | KAT8GRM5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137886-A | Agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-11 | — | — | US | disclosed |
| EP-0433001-A1 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-19 | — | — | EP | disclosed |