Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734509 | 0.98 | HSD11B1 (0.42) | HSD11B1SMN1; SMN2HCAR1ALDH1A1MEN1 | |
| SCHEMBL9734149 | 0.97 | TSHR (0.42) | HSD11B1SMN1; SMN2HCAR1ALDH1A1HTT | |
| SCHEMBL9724526 | 0.89 | HSD11B1 (0.46) | HSD11B1SMN1; SMN2ALDH1A1POLBHTT | |
| SCHEMBL9734258 | 0.89 | L3MBTL1 (0.43) | HSD11B1SMN1; SMN2TSHRLMNA | |
| SCHEMBL9734248 | 0.80 | CA1 (0.38) | HSD11B1HCAR1 | |
| SCHEMBL9865854 | 0.76 | HCAR1 (0.39) | SMN1; SMN2HCAR1LMNA | |
| SCHEMBL9865677 | 0.76 | HCAR1 (0.36) | HCAR1 | |
| SCHEMBL9733818 | 0.74 | POLB (0.46) | HSD11B1ALDH1A1POLBPKMTSHR | |
| SCHEMBL9866318 | 0.73 | ALDH1A1 (0.36) | SMN1; SMN2HCAR1ALDH1A1HTTLMNA | |
| SCHEMBL9866531 | 0.73 | POLB (0.36) | SMN1; SMN2HCAR1ALDH1A1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137886-A | Agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-11 | — | — | US | claimed |
| US-5137886-A | Agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-11 | — | — | US | disclosed |
| EP-0433001-A1 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-19 | — | — | EP | disclosed |