Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756855 | 0.76 | CES2 (0.41) | KDRGSK3BALDH1A1HTTHDAC3 | |
| SCHEMBL9756903 | 0.74 | RAB9A (0.44) | CLK4ALDH1A1HPGDHDAC8CNR2 | |
| SCHEMBL9756852 | 0.72 | MAPT (0.48) | PTPN1PTPN11ALDH1A1HPGDHTT | |
| SCHEMBL9756827 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HTTHDAC1MEN1KMT2A | |
| SCHEMBL9756986 | 0.72 | RAB9A (0.39) | PTPN1PTPN11ALDH1A1SMN1; SMN2 | |
| SCHEMBL9756984 | 0.71 | GAA (0.38) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL9756889 | 0.69 | LMNA (0.42) | PIM1CLK2DYRK1APIM3ALDH1A1 | |
| SCHEMBL28226880 | 0.67 | PTPN1 (0.49) | PTPN1PTPN11NSD2ALDH1A1HTT | |
| SCHEMBL23193358 | 0.67 | NCF1 (0.50) | PTPN1PTPN11NSD2DNMT1DNMT3L | |
| SCHEMBL9756896 | 0.67 | CES2 (0.38) | CDK2HPGDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | claimed |