Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757082 | 0.88 | ELANE (0.44) | PLK1ELANEKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9757118 | 0.79 | CYP4F2 (0.49) | CYP4F2CYP4A11PLK1CA12CA2 | |
| SCHEMBL9756985 | 0.74 | PLK1 (0.46) | PLK1ELANECA12CA2CA7 | |
| SCHEMBL17205196 | 0.74 | SMN1; SMN2 (0.49) | KDM4ESMN1; SMN2ALDH1A1MAOBMAOA | |
| SCHEMBL31745175 | 0.74 | CYP1A2 (0.46) | PLK1CA12CA2CA7CA9 | |
| SCHEMBL3611112 | 0.73 | AGPAT2 (0.49) | RXFP1KDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9757020 | 0.73 | FAAH (0.53) | ELANECA12CA2CA7CA9 | |
| SCHEMBL3621004 | 0.73 | RAB9A (0.53) | GAAKDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9757062 | 0.72 | MAOA (0.54) | GAACA12CA2CA7CA9 | |
| SCHEMBL14897791 | 0.71 | ALDH1A1 (0.48) | CA12CA2CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |