Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799313 | 0.89 | TUBB4A (0.38) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9799824 | 0.81 | NPC1 (0.35) | CYP1A2MEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL9799267 | 0.79 | CYP3A4 (0.46) | ALDH1A1ATMKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL9799541 | 0.77 | PTGS2 (0.39) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9833569 | 0.72 | TUBB4A (0.35) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL16382429 | 0.68 | ATM (0.58) | ATMKDM4ECYP1A2CYP3A4KMT2A | |
| SCHEMBL9799522 | 0.67 | TUBB4A (0.39) | SMN1; SMN2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9799232 | 0.67 | OPRM1 (0.40) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MEN1 | |
| SCHEMBL9830311 | 0.67 | CYP1A2 (0.40) | ALDH1A1ATMKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL6986357 | 0.67 | ALDH1A1 (0.61) | ALDH1A1ATMKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298703-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4946862-A | Thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0298703-A1 | A thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-01-11 | — | — | EP | disclosed |