Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48083 | 0.84 | KDM4E (0.44) | ABCG2KDM4ECYP3A4ALDH1A1MAPT | |
| SCHEMBL305332 | 0.74 | KDM4E (0.38) | ABCG2KDM4ECYP3A4MAPTCYP2C9 | |
| SCHEMBL10179796 | 0.74 | CTRC (0.38) | ABCG2KDM4ECYP3A4MAPTPTGS1 | |
| SCHEMBL2468591 | 0.74 | ABCG2 (0.40) | ABCG2KDM4ECYP3A4ALDH1A1MAPT | |
| SCHEMBL7128881 | 0.74 | PTGS1 (0.43) | ABCG2KDM4ECYP3A4ALDH1A1MAPT | |
| SCHEMBL15161586 | 0.70 | ABCG2 (0.41) | ABCG2KDM4ECYP3A4ALDH1A1MAPT | |
| SCHEMBL5492196 | 0.69 | ADORA3 (0.39) | ABCG2KDM4ECYP3A4ALDH1A1MAPT | |
| SCHEMBL22356152 | 0.69 | KDM4E (0.44) | KDM4ECYP3A4ALDH1A1MAPTCYP2C9 | |
| SCHEMBL2719464 | 0.69 | TDO2 (0.42) | KDM4ECYP3A4MAPTPTGS2PTGS1 | |
| SCHEMBL2721048 | 0.69 | KDM4E (0.35) | ABCG2KDM4ECYP3A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963428-B1 | Bucillamine prodrugs, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2018-05-08 | — | — | US | claimed |
| US-8658639-B2 | N-substituted-cyclic amino derivative | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-02-25 | — | — | US | claimed |
| US-20120122773-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-17 | — | — | US | claimed |
| EP-2447264-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-05-02 | — | — | EP | claimed |
| US-7205291-B2 | High mouth absorption; antibiotics against gramnegative, grampositive bacteria espscially Staphlococcus pneumonia, Hemophilus influenza | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-17 | — | — | US | claimed |
| US-6664008-B1 | Comprising solute, cyclic carbonate solvent, and separator; lithium batteries | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-12-16 | — | — | US | claimed |
| WO-2023098426-A1 | 7-(NAPHTHALENE-L-YL)PYRIDO[4,3-D]PYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2023-06-08 | — | — | WO | disclosed |
| CN-110117285-B | Inhibitors of influenza virus replication and uses thereof | 广东东阳光药业有限公司 | 2023-02-03 | — | — | CN | disclosed |
| US-9963428-B1 | Bucillamine prodrugs, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2018-05-08 | — | — | US | disclosed |
| EP-1892789-B1 | LITHIUM SECONDARY BATTERY | MITSUBISHI CHEM CORP (JP) | 2018-02-28 | — | — | EP | disclosed |
| US-9598354-B2 | Fumarate compounds, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2017-03-21 | — | — | US | disclosed |
| US-20160318848-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | Nguyen, Mark Quang (US) | 2016-11-03 | — | — | US | disclosed |
| US-8946144-B2 | Phosphonated glycopeptide and lipoglycopeptide antibiotics and uses thereof for the prevention and treatment of bone and joint infections | THE MEDICINES COMPANY (US) | 2015-02-03 | — | — | US | disclosed |
| EP-0090344-A1 | 1,3-Dioxolen-2-one derivatives and process for production thereof | KANEBO, LTD. (JP) | 1983-10-05 | — | — | EP | disclosed |
| US-4389408-A | ANTIBIOTICS CONTAINING A 1,3-DIOXOLENE OR DERIVATIVE RING | KANEBO LTD. (JP) | 1983-06-21 | — | — | US | disclosed |
| EP-0078413-A1 | Process for producing brominated 1,3-dioxolen-2-ones | KANEBO, LTD. (JP) | 1983-05-11 | — | — | EP | disclosed |
| EP-0069962-A1 | Novel ester of 1,1-dioxopenicillanic acid, process for production thereof, and use thereof as beta-lactamase inhibitor | KANEBO, LTD. (JP) | 1983-01-19 | — | — | EP | disclosed |
| EP-0061206-A1 | 6-Aminopenicillanic acid esters and their use for producing new ampicillin esters | KANEBO, LTD. (JP) | 1982-09-29 | — | — | EP | disclosed |
| US-4342693-A | USED FOR INTRODUCING PROTECTIVE GROUPS ON PHARMECUTICALS AND OTHERS | KANEBO LTD. (JP) | 1982-08-03 | — | — | US | disclosed |
| EP-0039477-A1 | Use of 1,3-Dioxolen-2-one derivatives | KANEBO, LTD. (JP) | 1981-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318848-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | FH, FPGS, APC | ABCG2 618/4885BRD4 3029/4885BRD2 2706/4885 |
| US-20120122773-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | REN, AGTR1, AGTR2 | ABCG2 1108/4885BRD4 243/4885BRD2 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.