Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834295 | 0.86 | NAAA (0.43) | TAAR1NR3C2 | |
| SCHEMBL9833469 | 0.84 | HDAC1 (0.46) | HDAC1HDAC8TAAR1NR3C2 | |
| SCHEMBL9832892 | 0.79 | NAAA (0.37) | FFAR4 | |
| SCHEMBL9834514 | 0.78 | HRH1 (0.41) | — | |
| SCHEMBL9832110 | 0.77 | TDP1 (0.41) | — | |
| SCHEMBL9832722 | 0.76 | MPO (0.39) | HDAC1TAAR1NR3C2 | |
| SCHEMBL30412030 | 0.75 | EPHX1 (0.59) | HDAC1HDAC8EPHX1AURKATAAR1 | |
| SCHEMBL9833135 | 0.75 | CNR1 (0.40) | HDAC1DHODH | |
| SCHEMBL249437 | 0.74 | EPHX1 (0.61) | HDAC1HDAC8EPHX1AURKATAAR1 | |
| SCHEMBL7150587 | 0.73 | MAPT (0.60) | HDAC1HDAC8EPHX1TAAR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129846-B1 | (3-AMINO-1H-PYRAZOL-4-YL)(ARYL)METHANONES | AMERICAN CYANAMID COMPANY (US) | 1991-05-08 | — | — | EP | claimed |