Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.40 |
| ▸ | CNR2 | P34972 | 8/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837576 | 0.88 | ALOX5 (0.46) | — | |
| SCHEMBL9833350 | 0.86 | TUBB4A (0.41) | CYP19A1 | |
| SCHEMBL9834740 | 0.83 | ALOX5 (0.44) | GLSCYP19A1 | |
| SCHEMBL9832110 | 0.81 | TDP1 (0.41) | GLS | |
| SCHEMBL9834514 | 0.80 | HRH1 (0.41) | — | |
| SCHEMBL9833469 | 0.80 | HDAC1 (0.46) | HDAC1HDAC6GLS | |
| SCHEMBL9833181 | 0.79 | HDAC3 (0.44) | HDAC1HDAC6 | |
| SCHEMBL9832892 | 0.79 | NAAA (0.37) | GLS | |
| SCHEMBL9833192 | 0.72 | ALDH1A1 (0.37) | HDAC1HDAC6GLS | |
| SCHEMBL5275656 | 0.71 | CNR1 (0.53) | CNR1CNR2HDAC1HDAC6PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129846-B1 | (3-AMINO-1H-PYRAZOL-4-YL)(ARYL)METHANONES | AMERICAN CYANAMID COMPANY (US) | 1991-05-08 | — | — | EP | claimed |