Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833469 | 0.87 | HDAC1 (0.46) | NAAAGLSDAOTAAR1NR3C2 | |
| SCHEMBL9832892 | 0.86 | NAAA (0.37) | NAAAGLSFAAH | |
| SCHEMBL9833331 | 0.86 | HDAC1 (0.47) | TAAR1NR3C2 | |
| SCHEMBL9832722 | 0.81 | MPO (0.39) | GLSDAOTAAR1NR3C2 | |
| SCHEMBL9834514 | 0.80 | HRH1 (0.41) | NAAAFAAHDAGLA | |
| SCHEMBL9832110 | 0.79 | TDP1 (0.41) | NAAAGLSFAAH | |
| SCHEMBL9833135 | 0.77 | CNR1 (0.40) | GLS | |
| SCHEMBL9833192 | 0.75 | ALDH1A1 (0.37) | GLSPOLB | |
| SCHEMBL9832047 | 0.75 | HRH1 (0.45) | NAAAGLS | |
| SCHEMBL1206928 | 0.71 | MAPT (0.66) | NAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129846-B1 | (3-AMINO-1H-PYRAZOL-4-YL)(ARYL)METHANONES | AMERICAN CYANAMID COMPANY (US) | 1991-05-08 | — | — | EP | claimed |