Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 7/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836619 | 0.91 | CXCR4 (0.42) | TSHRCXCR4LTA4HCHRM2CHRM4 | |
| SCHEMBL9836638 | 0.79 | CYP2C19 (0.41) | ADRA2CADRA2AADRA2BTSHRCHRM2 | |
| SCHEMBL9837035 | 0.79 | OPRL1 (0.42) | CXCR4LTA4H | |
| SCHEMBL9835190 | 0.77 | HTR1A (0.35) | ADRA2CHRH3ALOX15LTA4HCHRM2 | |
| SCHEMBL9834580 | 0.76 | HRH1 (0.36) | ALOX15TSHRCXCR4CHRM2CHRM4 | |
| SCHEMBL9835645 | 0.76 | ALDH1A1 (0.37) | ADRA2CHRH3ALOX15TSHRLTA4H | |
| SCHEMBL9836246 | 0.72 | MTNR1A (0.40) | TSHR | |
| SCHEMBL9834815 | 0.70 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9835161 | 0.68 | HRH3 (0.38) | ADRA2CADRA2AADRA2BHRH3ALOX15 | |
| SCHEMBL9837005 | 0.68 | MAOA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129879-B1 | A [1] benzepino(3,4-b)pyridine derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-09-11 | — | — | EP | claimed |
| US-4547496-A | Antiulcer [1] benzepino[3,4-b]pyridine and compositions | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-10-15 | — | — | US | claimed |