Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.57 |
| ▸ | CA2 | P00918 | 12/20 | 0.57 |
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320423 | 0.86 | CA1 (0.56) | CA1CA2CA12CA9HTT | |
| SCHEMBL9864427 | 0.84 | CA1 (0.55) | CA1CA2CA12CA9HTT | |
| Potassium Ion SCHEMBL11516871 | 0.81 | CA1 (0.52) | CA1CA2CA12CA9HTT | |
| SCHEMBL29466714 | 0.77 | CA1 (0.55) | CA1CA2CYP1A2CYP2C19MEN1 | |
| SCHEMBL8650426 | 0.76 | HTT (0.61) | CA1CA2CA12CA9HTT | |
| Potassium Ion SCHEMBL11522100 | 0.76 | ALDH1A1 (0.49) | CA1CA2HSD17B10MEN1KMT2A | |
| SCHEMBL8996041 | 0.75 | MAPT (0.59) | HTTHSD17B10CYP1A2CYP2C19JAK2 | |
| SCHEMBL11421956 | 0.75 | HTT (0.59) | CA1CA2CA12CA9HTT | |
| SCHEMBL8623425 | 0.75 | HSD17B10 (0.63) | HTTHSD17B10CYP1A2CYP2C19MEN1 | |
| SCHEMBL1260084 | 0.75 | KMT2A (0.70) | HTTHSD17B10CYP1A2CYP2C19JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049477-A | Image forming, etching, plating | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-17 | — | — | US | disclosed |