Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735650 | 0.80 | HSD11B1 (0.43) | HCAR1HSD11B1 | |
| SCHEMBL9734509 | 0.79 | HSD11B1 (0.42) | HCAR1HSD11B1 | |
| SCHEMBL9734149 | 0.78 | TSHR (0.42) | HCAR1HSD11B1 | |
| SCHEMBL9865854 | 0.77 | HCAR1 (0.39) | CA1CA2HCAR1HTR1DHTR1B | |
| SCHEMBL9865677 | 0.77 | HCAR1 (0.36) | CA1CA2HCAR1NFE2L2HTR1D | |
| SCHEMBL9734258 | 0.76 | L3MBTL1 (0.43) | HSD11B1 | |
| SCHEMBL9724526 | 0.76 | HSD11B1 (0.46) | HSD11B1 | |
| SCHEMBL9866318 | 0.74 | ALDH1A1 (0.36) | HCAR1NFE2L2 | |
| SCHEMBL9866531 | 0.74 | POLB (0.36) | HCAR1NFE2L2 | |
| SCHEMBL10745662 | 0.74 | TXNRD1 (0.34) | HCAR1NFE2L2HTR1DHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137886-A | Agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-11 | — | — | US | disclosed |
| EP-0433001-A1 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-19 | — | — | EP | disclosed |