SCHEMBL9870770

SCHEMBL9870770

Cc1ccc(S(=O)(=O)Oc2ccc(Cl)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.68
ENPP3 O14638 2/20 0.68
ENPP1 P22413 2/20 0.68
ENPP2 Q13822 1/20 0.68
KMT2A Q03164 4/20 0.60
MEN1 O00255 3/20 0.60
ALPL P05186 1/20 0.51
ALPI P09923 1/20 0.51
CA2 P00918 4/20 0.50
CA1 P00915 2/20 0.50
CA9 Q16790 2/20 0.50
CA12 O43570 2/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.50
PPARG P37231 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12584886 1.00 TDP1 (0.68) TDP1ENPP3ENPP1ENPP2KMT2A
SCHEMBL17287655 0.95 ENPP3 (0.63) TDP1ENPP3ENPP1ENPP2KMT2A
Chlorfenson SCHEMBL7194888 0.90 TDP1 (0.81) TDP1ENPP3ENPP1ENPP2KMT2A
Chlorfenson SCHEMBL116752 0.90 TDP1 (0.81) TDP1ENPP3ENPP1ENPP2KMT2A
SCHEMBL9852204 0.90 MEN1 (0.60) TDP1ENPP3ENPP1ENPP2KMT2A
SCHEMBL18179825 0.90 MEN1 (0.60) TDP1ENPP3ENPP1ENPP2KMT2A
SCHEMBL4126086 0.90 MEN1 (0.60) TDP1ENPP3ENPP1ENPP2KMT2A
Iodide SCHEMBL22068772 0.88 CA2 (0.59) TDP1ENPP3ENPP1ENPP2KMT2A
SCHEMBL4084466 0.85 MEN1 (0.53) TDP1ENPP3ENPP1ENPP2KMT2A
SCHEMBL941647 0.85 GAA (0.64) TDP1ENPP3ENPP1ENPP2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118715015-A Selective PHD1 inhibitor compounds, compositions and methods of use 阿克比治疗有限公司 2024-09-27 CN disclosed
US-10463391-B2 Magnetic ferrocenyl-functionalized nanoparticle KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2019-11-05 US disclosed
US-10370397-B2 Phosphine substituted ferrocenyl complex Kind Fahd University of Petroleum and Minerals (SA) 2019-08-06 US disclosed
US-20190031697-A1 PHOSPHINE SUBSTITUTED FERROCENYL COMPLEX KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2019-01-31 US disclosed
US-20190029718-A1 MAGNETIC FERROCENYL-FUNCTIONALIZED NANOPARTICLE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2019-01-31 US disclosed
US-10150109-B2 Palladium(II)-silica supported catalyst KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-12-11 US disclosed
US-10150111-B2 Method for catalytic synthesis of cinnamic acid with catalyst recycle KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-12-11 US disclosed
US-10150110-B2 Method for making and using a solid-supported catalyst KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-12-11 US disclosed
US-20180326409-A1 METHOD FOR MAKING AND USING A SOLID-SUPPORTED CATALYST KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-11-15 US disclosed
US-20180326410-A1 METHOD FOR CATALYTIC SYNTHESIS OF CINNAMIC ACID WITH CATALYST RECYCLE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-11-15 US disclosed
US-10125159-B2 Functionalized magnetic nanoparticle, a catalyst, a method for forming C—C bonds KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-11-13 US disclosed
US-10058856-B2 Method for palladium-catalyzed cinammic acid formation KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-08-28 US disclosed
US-20180200705-A1 METHOD FOR PALLADIUM-CATALYZED CINAMMIC ACID FORMATION KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-07-19 US disclosed
US-20180200706-A1 PALLADIUM(II)-SILICA SUPPORTED CATALYST KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-07-19 US disclosed
US-9956550-B2 Solid-supported palladium(II) complex for catalyzing Mizoroki-Heck coupling reactions and a method thereof KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-05-01 US disclosed
US-20180099987-A1 FUNCTIONALIZED MAGNETIC NANOPARTICLE, A CATALYST, A METHOD FOR FORMING C-C BONDS KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-04-12 US disclosed
US-20180065117-A1 SOLID-SUPPORTED PALLADIUM(II) COMPLEX FOR CATALYZING MIZOROKI-HECK COUPLING REACTIONS AND A METHOD THEREOF KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-03-08 US disclosed
US-5049558-A Quaternized nitrogen-heterocycle substituted IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-09-17 US disclosed
EP-0164944-B1 CEPHALOSPORIN DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-07-11 EP disclosed
EP-0164944-A1 Cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10150109-B2 Palladium(II)-silica supported catalyst PDK2, SIK2, SIK1 TDP1 4356/4885ENPP3 3759/4885ENPP1 3952/4885
US-20180099987-A1 FUNCTIONALIZED MAGNETIC NANOPARTICLE, A CATALYST, A METHOD FOR FORMING C-C BONDS MSN, COIL, NSFL1C TDP1 4863/4885ENPP3 3953/4885ENPP1 4451/4885
US-20180326409-A1 METHOD FOR MAKING AND USING A SOLID-SUPPORTED CATALYST AOC1, SOD1, PDK2 TDP1 3883/4885ENPP3 3414/4885ENPP1 3546/4885
US-20180326410-A1 METHOD FOR CATALYTIC SYNTHESIS OF CINNAMIC ACID WITH CATALYST RECYCLE DDT, PDK2, CLK2 TDP1 4209/4885ENPP3 3088/4885ENPP1 3194/4885
US-10058856-B2 Method for palladium-catalyzed cinammic acid formation ME1, CLK2, DDT TDP1 4162/4885ENPP3 4040/4885ENPP1 4058/4885
US-10370397-B2 Phosphine substituted ferrocenyl complex FECH, PHOSPHO1, FTH1 TDP1 4869/4885ENPP3 2460/4885ENPP1 2917/4885
US-20190031697-A1 PHOSPHINE SUBSTITUTED FERROCENYL COMPLEX FECH, FOLR1, FOLR2 TDP1 4655/4885ENPP3 2188/4885ENPP1 2539/4885
US-20180200706-A1 PALLADIUM(II)-SILICA SUPPORTED CATALYST PDK2, SIK2, SIK1 TDP1 4356/4885ENPP3 3759/4885ENPP1 3952/4885
US-20180200705-A1 METHOD FOR PALLADIUM-CATALYZED CINAMMIC ACID FORMATION ME1, CLK2, DDT TDP1 4162/4885ENPP3 4040/4885ENPP1 4058/4885
US-10150111-B2 Method for catalytic synthesis of cinnamic acid with catalyst recycle DDT, PDK2, CLK2 TDP1 4209/4885ENPP3 3088/4885ENPP1 3194/4885
US-20180065117-A1 SOLID-SUPPORTED PALLADIUM(II) COMPLEX FOR CATALYZING MIZOROKI-HECK COUPLING REACTIONS AND A METHOD THEREOF DDT, PDK2, DNAJA2 TDP1 4207/4885ENPP3 3612/4885ENPP1 3813/4885
US-10150110-B2 Method for making and using a solid-supported catalyst AOC1, SOD1, PDK2 TDP1 3883/4885ENPP3 3414/4885ENPP1 3546/4885
US-10125159-B2 Functionalized magnetic nanoparticle, a catalyst, a method for forming C—C bonds MSN, COIL, CORO1C TDP1 4867/4885ENPP3 3904/4885ENPP1 4447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.