SCHEMBL987539

SCHEMBL987539

C[Si](C)(C)C#CCCCCl

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL767325 0.92 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL21484050 0.90 ALDH1A1 (0.36) TSHRALDH1A1
SCHEMBL10429374 0.90 ALDH1A1 (0.36) TSHRALDH1A1
SCHEMBL10429387 0.90 ALDH1A1 (0.36) TSHRALDH1A1
SCHEMBL9540191 0.83
SCHEMBL16420274 0.83 RAB9A (0.33)
SCHEMBL20639270 0.83
SCHEMBL31725737 0.80 RAB9A (0.38)
SCHEMBL18692026 0.80
SCHEMBL23532681 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 US disclosed
US-20250221953-A1 TRANS-VACCENIC ACID (TVA) AND DERIVATIVES THEREOF IN T CELL-BASED CANCER THERAPIES THE UNIVERSITY OF CHICAGO 2025-07-10 US disclosed
US-12178851-B2 Methods for administering STING agonists GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2024-12-31 US disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 US disclosed
US-11970480-B2 Heterocyclic amides useful as protein modulators GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2024-04-30 US disclosed
WO-2023192947-A2 TRANS-VACCENIC ACID (TVA) AND DERIVATIVES THEREOF IN T CELL-BASED CANCER THERAPIES THE UNIVERSITY OF CHICAGO (US) 2023-10-05 WO disclosed
US-20230295827-A1 COATINGS AND COATED SURFACES INCLUDING LOW-SURFACE ENERGY INORGANIC PARTICLES MAXTERIAL INC (US) 2023-09-21 US disclosed
CN-111417630-B Modulators of interferon gene stimulating factor (STING) 葛兰素史克知识产权开发有限公司 2023-06-06 CN disclosed
CN-110167599-B Compounds comprising self-sacrificing linking groups incorporating beta-galactosides 英托赛尔公司 2023-05-16 CN disclosed
US-20230071675-A1 Heterocyclic Amides Useful as Protein Modulators GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2023-03-09 US disclosed
EP-2125859-B1 ESTRATRIENE DERIVATIVES AND THEIR USES AS 17BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS ABBOTT PRODUCTS GMBH (DE) 2013-05-15 EP disclosed
US-8080540-B2 Therapeutically active triazoles and their use ABBOTT PRODUCTS GMBH (DE) 2011-12-20 US disclosed
US-20110020837-A1 Method for isolating or identifying a target protein interacting with a lipid in a cell UNIVERSITEIT UTRECHT HOLDING B.V. (NL) 2011-01-27 US disclosed
EP-2125859-A2 ESTRATRIENE DERIVATIVES AND THEIR USES AS 17BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS Solvay Pharmaceuticals GmbH (DE) 2009-12-02 EP disclosed
US-20080146531-A1 Therapeutically Active Triazoles and Their Use SOLVAY PHARMACEUTICALS GMBH (DE) 2008-06-19 US disclosed
WO-2008034796-A2 ESTRATRIENE DERIVATIVES AND THEIR USES AS 17BETA-HYDR0XYSTER0ID DEHYDROGENASE INHIBITORS SOLVAY PHARMACEUTICALS GMBH (DE) 2008-03-27 WO disclosed
US-5466710-A Heterobicycloalkanes as pesticidal compounds ROUSSEL UCLAF (FR) 1995-11-14 US disclosed
EP-0300797-B1 Pesticidal compounds ROUSSEL UCLAF (FR) 1995-10-04 EP disclosed
US-5116862-A Acetylenic trithiabicyclo(2.2.2)octanes THE WELLCOME FOUNDATION LIMITED (GB) 1992-05-26 US disclosed
EP-0300797-A1 Pesticidal compounds ROUSSEL UCLAF (FR) 1989-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11970480-B2 Heterocyclic amides useful as protein modulators RB1, RBBP5, RCC2 TSHR 1048/4885TDP1 1654/4885ALDH1A1 3511/4885
US-20250221953-A1 TRANS-VACCENIC ACID (TVA) AND DERIVATIVES THEREOF IN T CELL-BASED CANCER THERAPIES GPR65, GPR52, GPR84 TSHR 787/4885TDP1 4536/4885ALDH1A1 3369/4885
US-20080146531-A1 Therapeutically Active Triazoles and Their Use HSD17B2, HSD17B3, HSD17B1 TSHR 702/4885TDP1 1158/4885ALDH1A1 87/4885
US-20110020837-A1 Method for isolating or identifying a target protein interacting with a lipid in a cell PLIN5, PLIN1, PLIN3 TSHR 1564/4885TDP1 4301/4885ALDH1A1 3031/4885
US-20230071675-A1 Heterocyclic Amides Useful as Protein Modulators RB1, RBBP5, RCC2 TSHR 1048/4885TDP1 1654/4885ALDH1A1 3511/4885
US-12178851-B2 Methods for administering STING agonists STING1, CGAS, TLR9 TSHR 2499/4885TDP1 286/4885ALDH1A1 4653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.