Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23709159 | 0.82 | LMNA (0.52) | HDAC1LMNATYRSRD5A2TSHR | |
| SCHEMBL18644564 | 0.81 | NOS3 (0.39) | LMNATSHRMAPTALDH1A1KMT2A | |
| SCHEMBL7965283 | 0.79 | LMNA (0.55) | HDAC1LMNATYRSRD5A2TSHR | |
| SCHEMBL18537001 | 0.78 | HDAC1 (0.48) | HDAC1LMNATYRSRD5A2TSHR | |
| SCHEMBL421322 | 0.78 | NQO2 (0.60) | HDAC1LMNATYRSRD5A2NQO2 | |
| Hydrochloric Acid SCHEMBL22712464 | 0.76 | NQO2 (0.58) | HDAC1LMNATYRSRD5A2NQO2 | |
| SCHEMBL292571 | 0.76 | LMNA (0.57) | HDAC1LMNATYRSRD5A2TSHR | |
| SCHEMBL397829 | 0.75 | EPHX2 (0.65) | HDAC1LMNATYRSRD5A2MAPT | |
| SCHEMBL465848 | 0.75 | TSHR (0.52) | HDAC1LMNATYRSRD5A2TSHR | |
| SCHEMBL11699186 | 0.75 | MAPT (0.50) | HDAC1LMNATYRSRD5A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020242719-A2 | INHIBITORS OF RNA-BINDING PROTEINS, COMPOSITIONS THEREOF, AND THERAPEUTIC USES THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2020-12-03 | — | — | WO | disclosed |
| US-10017691-B2 | Organic electroluminescent element, display device and lighting device | Konica Minolta, Inc. (JP) | 2018-07-10 | — | — | US | disclosed |
| US-9266828-B2 | Inhibitors of Furin and other pro-protein convertases | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2016-02-23 | — | — | US | disclosed |
| US-20150148284-A1 | Controlled Release of Phenolic Opioids | PHARMACOFORE, INC. | 2015-05-28 | — | — | US | disclosed |
| US-20150073054-A1 | INHIBITORS OF FURIN AND OTHER PRO-PROTEIN CONVERTASES | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | 2015-03-12 | — | — | US | disclosed |
| US-20150051138-A1 | INHIBITORS OF FURIN AND OTHER PRO-PROTEIN CONVERTASES | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2015-02-19 | — | — | US | disclosed |
| US-8921418-B2 | Controlled release of phenolic opioids | SIGNATURE THERAPEUTICS, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20120270894-A1 | Controlled Release of Phenolic Opioids | 3I, LP | 2012-10-25 | — | — | US | disclosed |
| US-20120142718-A1 | N-17-Alkylated Prodrugs of Opioids | SIGNATURE THERAPEUTICS, INC. | 2012-06-07 | — | — | US | disclosed |
| US-20070218136-A1 | New mandelic acid derivatives and their use as thrombin inhibitors | ASTRAZENECA AB | 2007-09-20 | — | — | US | disclosed |
| US-20070202174-A1 | New mandelic acid derivatives and their use as thrombin inhibitors | ASTRAZENECA AB | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070202174-A1 | New mandelic acid derivatives and their use as thrombin inhibitors | TFPI, F2R, F2 | HDAC1 1818/4885LMNA 1869/4885TYR 427/4885 |
| US-20120270894-A1 | Controlled Release of Phenolic Opioids | OPRK1, OPRM1, OPRD1 | HDAC1 744/4885LMNA 4070/4885TYR 200/4885 |
| US-10017691-B2 | Organic electroluminescent element, display device and lighting device | L1CAM, ELOVL1, LAGE3 | HDAC1 3771/4885LMNA 3814/4885TYR 25/4885 |
| US-20150148284-A1 | Controlled Release of Phenolic Opioids | OPRK1, OPRM1, OPRD1 | HDAC1 744/4885LMNA 4070/4885TYR 200/4885 |
| US-20150051138-A1 | INHIBITORS OF FURIN AND OTHER PRO-PROTEIN CONVERTASES | FURIN, PREP, PCSK6 | HDAC1 430/4885LMNA 558/4885TYR 4197/4885 |
| US-20120142718-A1 | N-17-Alkylated Prodrugs of Opioids | OPRM1, OPRD1, OPRL1 | HDAC1 1051/4885LMNA 2758/4885TYR 2245/4885 |
| US-20070218136-A1 | New mandelic acid derivatives and their use as thrombin inhibitors | TFPI, F2R, F2 | HDAC1 1818/4885LMNA 1869/4885TYR 427/4885 |
| US-20150073054-A1 | INHIBITORS OF FURIN AND OTHER PRO-PROTEIN CONVERTASES | FURIN, PREP, PCSK6 | HDAC1 430/4885LMNA 558/4885TYR 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.