Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15415736 | 0.84 | LMNA (0.41) | CYP1A2MAPK1SMN1; SMN2LMNASLC22A6 | |
| SCHEMBL2113300 | 0.77 | GLA (0.38) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| SCHEMBL10389443 | 0.77 | HSD17B10 (0.32) | — | |
| SCHEMBL10813588 | 0.75 | KEAP1 (0.34) | SMN1; SMN2CYP2D6 | |
| SCHEMBL27191526 | 0.72 | CYP1A2 (0.47) | CYP1A2MAPK1SMN1; SMN2LMNASLC22A6 | |
| SCHEMBL14288717 | 0.72 | HSD17B10 (0.31) | CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL371279 | 0.72 | GNAI3 (0.33) | CYP1A2MAPK1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL4643767 | 0.70 | — | — | |
| Glutarate SCHEMBL4060585 | 0.69 | SLC22A6 (0.58) | CYP1A2MAPK1SMN1; SMN2LMNASLC22A6 | |
| Adipic Acid SCHEMBL4049809 | 0.69 | LMNA (0.58) | LMNASLC22A6TSHRBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9832996-B2 | Use of sarmentine and its analogues with an herbicide, and compositions thereof | MARRONE BIO INNOVATIONS, INC. (US) | 2017-12-05 | — | — | US | disclosed |
| US-20170196222-A9 | Use of Sarmentine and Its Analogues With an Herbicide, and Compositions Thereof | PRO FARM GROUP, INC. | 2017-07-13 | — | — | US | disclosed |
| EP-2710892-B1 | Use of sarmentine and its analogs for controlling weeds | MARRONE BIO INNOVATIONS INC (US) | 2016-12-14 | — | — | EP | disclosed |
| US-20160212999-A1 | Use of Sarmentine and Its Analogues With an Herbicide, and Compositions Thereof | MARRONE BIO INNOVATIONS INC (US) | 2016-07-28 | — | — | US | disclosed |
| US-9179675-B2 | Use of sarmentine and its analogs for controlling plant pests | MARRONE BIO INNOVATIONS, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-20150111749-A1 | USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS | PRO FARM GROUP, INC. | 2015-04-23 | — | — | US | disclosed |
| WO-2015050705-A1 | USE OF SARMENTINE AND ITS ANALOGUES WITH AN HERBICIDE, AND COMPOSITIONS THEREOF | MARRONE BIO INNOVATIONS, INC. (US) | 2015-04-09 | — | — | WO | disclosed |
| US-8957000-B2 | Use of sarmentine and its analogs for controlling plant pests | MARRONE BIO INNOVATIONS, INC. (US) | 2015-02-17 | — | — | US | disclosed |
| EP-2710892-A2 | Use of sarmentine and its analogs for controlling plant pests | Marrone Bio Innovations, Inc. (US) | 2014-03-26 | — | — | EP | disclosed |
| US-20130281294-A1 | USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS | PRO FARM GROUP, INC. | 2013-10-24 | — | — | US | disclosed |
| US-8466192-B2 | Use of sarmentine and its analogs for controlling plant pests | MARRONE BIO INNOVATIONS, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| EP-2456305-A2 | USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS | Marrone Bio Innovations, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011011415-A2 | USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS | MARRONE BIO INNOVATIONS, INC. (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20110021358-A1 | USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS | MARRONE BIO INNOVATIONS, INC. (US) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281294-A1 | USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS | SARM1, SMOX, STOM | CYP1A2 1920/4885MAPK1 2622/4885SMN1; SMN2 1773/4885 |
| US-20160212999-A1 | Use of Sarmentine and Its Analogues With an Herbicide, and Compositions Thereof | DDT, SRM, SMOX | CYP1A2 231/4885MAPK1 3183/4885SMN1; SMN2 2934/4885 |
| US-20170196222-A9 | Use of Sarmentine and Its Analogues With an Herbicide, and Compositions Thereof | DDT, SRM, SMOX | CYP1A2 231/4885MAPK1 3183/4885SMN1; SMN2 2934/4885 |
| US-20110021358-A1 | USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS | SARM1, SMOX, STOM | CYP1A2 1920/4885MAPK1 2622/4885SMN1; SMN2 1773/4885 |
| US-20150111749-A1 | USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS | SARM1, SMOX, STOM | CYP1A2 1920/4885MAPK1 2622/4885SMN1; SMN2 1773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.