Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081302 | 0.89 | TSHR (0.50) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL5077875 | 0.89 | TSHR (0.50) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL9153932 | 0.82 | TSHR (0.43) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL14763918 | 0.82 | TSHR (0.43) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL29074342 | 0.81 | ALDH1A1 (0.38) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL29205847 | 0.80 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL28718238 | 0.80 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL10201330 | 0.80 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL6569030 | 0.79 | — | — | |
| SCHEMBL3389649 | 0.78 | SMN1; SMN2 (0.48) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114308129-B | Catalyst composition for olefin alkoxycarbonylation and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2022-12-06 | — | — | CN | disclosed |
| CN-114308129-A | Catalyst composition for olefin alkoxycarbonylation and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2022-04-12 | — | — | CN | disclosed |
| CN-109952360-B | Quantum dot dispersion, self-luminous photosensitive resin composition, color filter manufactured using the same, and image display device | 东友精细化工有限公司 | 2022-03-22 | — | — | CN | disclosed |
| US-10696702-B2 | Propyl-bridged diphosphine ligands for alkoxycarbonylation | EVONIK OPERATIONS GMBH (DE) | 2020-06-30 | — | — | US | disclosed |
| CN-106432365-B | Ferrocenyl compounds and palladium catalysts based thereon for the alkoxycarbonylation of ethylenically unsaturated compounds | 赢创运营有限公司 | 2020-04-07 | — | — | CN | disclosed |
| US-20190248817-A1 | PROPYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION | EVONIK DEGUSSA GMBH (DE) | 2019-08-15 | — | — | US | disclosed |
| US-10077228-B2 | Ferrocene-based compounds and palladium catalysts based thereon for the alkoxycarbonylation of ethylenically unsaturated compounds | EVONIK DEGUSSA GMBH (DE) | 2018-09-18 | — | — | US | disclosed |
| EP-3121184-B1 | BENZENE-BASED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION | EVONIK DEGUSSA GMBH (DE) | 2018-09-12 | — | — | EP | disclosed |
| EP-3121186-B1 | FERROCENE-BASED COMPOUNDS AND PALLADIUM CATALYSTS BASED ON SAME FOR THE ALKOXYCARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2018-09-12 | — | — | EP | disclosed |
| US-9884844-B2 | Heterocyclic compounds and methods of use thereof | SUNOVION PHARMACEUTICALS, INC. (US) | 2018-02-06 | — | — | US | disclosed |
| US-20140243257-A1 | BENZIMIDAZOLE ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-08-28 | — | — | US | disclosed |
| US-20130090364-A1 | ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130059801-A1 | FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE | CATABASIS PHARMACEUTICALS, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-8354419-B2 | Benzimidazole analogues for the treatment or prevention of flavivirus infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-01-15 | — | — | US | disclosed |
| US-8198016-B2 | Patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-06-12 | — | — | US | disclosed |
| US-20120027803-A1 | BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-02-02 | — | — | US | disclosed |
| US-20110172238-A1 | BENZIMIDAZOLE ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED | 2011-07-14 | — | — | US | disclosed |
| US-20090286188-A1 | Patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20070117797-A1 | Alkylamino, arylamino, and sulfonamido cyclopentyl amide modulators of chemokine receptor activity | MERCK SHARP & DOHME CORP. | 2007-05-24 | — | — | US | disclosed |
| US-20070117797-A1 | Alkylamino, arylamino, and sulfonamido cyclopentyl amide modulators of chemokine receptor activity | MERCK SHARP & DOHME CORP. | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027803-A1 | BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | LIPA, CETP, APOB | TSHR 2854/4885HSD17B10 295/4885MGAM 2499/4885 |
| US-20190248817-A1 | PROPYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION | PPIP5K2, MVD, PNKP | TSHR 4036/4885HSD17B10 3945/4885MGAM 4650/4885 |
| US-20070117797-A1 | Alkylamino, arylamino, and sulfonamido cyclopentyl amide modulators of chemokine receptor activity | CCR7, ACKR3, CCR2 | TSHR 458/4885HSD17B10 2559/4885MGAM 3903/4885 |
| US-10077228-B2 | Ferrocene-based compounds and palladium catalysts based thereon for the alkoxycarbonylation of ethylenically unsaturated compounds | C5, C1S, ALOX12 | TSHR 531/4885HSD17B10 301/4885MGAM 4833/4885 |
| US-20130059801-A1 | FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE | FASN, FADS1, ELOVL5 | TSHR 2989/4885HSD17B10 200/4885MGAM 1443/4885 |
| US-10696702-B2 | Propyl-bridged diphosphine ligands for alkoxycarbonylation | PPIP5K2, MVD, PNKP | TSHR 4036/4885HSD17B10 3945/4885MGAM 4650/4885 |
| US-20140243257-A1 | BENZIMIDAZOLE ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | BRI3BP, BLVRB, BRIX1 | TSHR 1952/4885HSD17B10 3405/4885MGAM 2456/4885 |
| US-20130090364-A1 | ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | BLVRB, C1QBP, RRP1B | TSHR 1605/4885HSD17B10 3392/4885MGAM 3038/4885 |
| US-20110172238-A1 | BENZIMIDAZOLE ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | BRI3BP, BLVRB, BRIX1 | TSHR 1952/4885HSD17B10 3405/4885MGAM 2456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.