Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354332 | 0.83 | GABRA1 (0.42) | ADORA2AADORA1HCRTR1HCRTR2TAAR1 | |
| SCHEMBL305910 | 0.83 | ADORA2A (0.46) | ADORA2AADORA1HCRTR1HCRTR2DRD2 | |
| Propionic Acid SCHEMBL2687317 | 0.79 | DRD2 (0.40) | ADORA2AADORA1HCRTR1HCRTR2DRD2 | |
| SCHEMBL25015239 | 0.78 | ALDH1A1 (0.40) | ADORA2AADORA1TAAR1DRD2HTR1A | |
| Propionic Acid SCHEMBL2686240 | 0.77 | NOTUM (0.41) | ADORA2AADORA1HCRTR1HCRTR2DRD2 | |
| Propionic Acid SCHEMBL2637824 | 0.77 | ADORA2A (0.45) | ADORA2AADORA1HCRTR1HCRTR2DRD2 | |
| SCHEMBL18665582 | 0.77 | KDM4E (0.43) | ADORA2AADORA1DRD2HTR1AMTNR1A | |
| SCHEMBL4898912 | 0.77 | ALDH1A1 (0.44) | ADORA2AADORA1TAAR1DRD2HTR1A | |
| SCHEMBL31170723 | 0.77 | ALDH1A1 (0.44) | ADORA2AADORA1TAAR1DRD2HTR1A | |
| SCHEMBL21316386 | 0.76 | ADORA2A (0.38) | ADORA2AADORA1DRD2HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-10-20 | — | — | US | disclosed |
| US-8198448-B2 | Fused heterocyclic derivatives and methods of use | AMGEN INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20090318436-A1 | Fused heterocyclic derivatives and methods of use | AMGEN INC. (US) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318436-A1 | Fused heterocyclic derivatives and methods of use | HGF, HGFAC, MET | ADORA2A 2496/4885ADORA1 3969/4885HCRTR1 3990/4885 |
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | ADORA2A 1225/4885ADORA1 2043/4885HCRTR1 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.