SCHEMBL9914077

SCHEMBL9914077

CC(C)[C@@H]1OC(CO)[C@H](O)[C@H](O)C1O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ LGALS1 P09382 2/20 0.47
▸ LGALS3 P17931 2/20 0.47
▸ LGALS9 O00182 1/20 0.47
▸ LGALS8 O00214 1/20 0.47
▸ PYGB P11216 2/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ MAPT P10636 1/20 0.42
▸ GAA P10253 2/20 0.41
▸ ALDH1A1 P00352 3/20 0.39
▸ TSHR P16473 2/20 0.39
▸ LMNA P02545 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14191378 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL14191382 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL14025371 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL14278435 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL10176794 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL12221718 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL23640046 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL20340506 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL21339944 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL12242433 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8PYGB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11780872-B2 Oligosaccharide analytical standards UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2023-10-10 — — US disclosed
US-20230242499-A1 COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE SYSMEX CORPORATION (JP) 2023-08-03 — — US disclosed
US-20180140581-A1 METABOLICALLY PROGRAMMED METAL CHELATORS AND USES THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2018-05-24 — — US disclosed
US-20160153989-A1 SELECTION OF BIOLOGICAL OBJECTS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2016-06-02 — — US disclosed
US-20130012466-A1 COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-01-10 — — US disclosed
US-20130012466-A1 COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-01-10 — — US disclosed
US-20120264924-A1 Glycorandomization and Production of Novel Novobiocin Analogs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-10-18 — — US disclosed
US-8232254-B2 Colchicine glycosylated to include a sugar moiety on a methoxyamino-appended colchicine; cytolysis equivalent to paclitaxel and doxorubicin; stabilizers of tubulin formation; anticarcinogenic -arthritic agents; Mediterranean fever, amyloidosis, scleroderma, irritable bowel syndrome or gout WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-07-31 — — US disclosed
US-8198419-B2 Glycorandomization and production of novel erythromycin analogs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-06-12 — — US disclosed
US-20110124850-A1 Glycorandomization and Production of Novel Vancomycin Analogs THORSON JON 2011-05-26 — — US disclosed
US-20080171787-A1 COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-07-17 — — US disclosed
US-7348309-B2 Glycorandomization and production of novel vancomycin analogs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-03-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080171787-A1 COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE TUBB6, TUBB, TUBA1C LGALS1 138/4885LGALS3 116/4885LGALS9 464/4885
US-20110124850-A1 Glycorandomization and Production of Novel Vancomycin Analogs NMT1, NMT2, B3GNT2 LGALS1 1838/4885LGALS3 1512/4885LGALS9 1928/4885
US-11780872-B2 Oligosaccharide analytical standards OSTC, FUT5, FUT6 LGALS1 427/4885LGALS3 312/4885LGALS9 260/4885
US-20180140581-A1 METABOLICALLY PROGRAMMED METAL CHELATORS AND USES THEREOF FECH, SLC19A1, SLC40A1 LGALS1 3977/4885LGALS3 4453/4885LGALS9 3026/4885
US-20130012466-A1 COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE TUBB6, TUBB, TUBA1C LGALS1 138/4885LGALS3 116/4885LGALS9 464/4885
US-20120264924-A1 Glycorandomization and Production of Novel Novobiocin Analogs NMT2, NMT1, NAMPT LGALS1 1415/4885LGALS3 1455/4885LGALS9 1916/4885
US-20230242499-A1 COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE JAK2, MPO, PEAK1 LGALS1 1779/4885LGALS3 1977/4885LGALS9 593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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